加拿大新近移民中与慢性乙型和丙型肝炎相关的住院:一项与移民行政数据相关的基于人群的队列研究

IF 2.7 2区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Health Reports Pub Date : 2022-06-15 DOI:10.25318/82-003-x202200600003-eng

Edward Ng, Jacklyn Quinlan, George Giovinazzo, Maria Syoufi, Dominique Elien Massenat, Claudia Sanmartin, Curtis Cooper

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引用次数: 3

摘要

背景:来自乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)流行国家的加拿大移民可能比加拿大出生的居民患肝脏相关疾病的风险更高。本研究比较了加拿大移民(1980年至2013年抵达加拿大)和长期居民(加拿大出生人口和1980年以前的移民)的HBV和hcv相关住院情况，旨在描述两组的疾病负担。方法:基于与1980- 2013年纵向移民数据库相关的2004/2005- 2013/2014年医院出院摘要数据库，本描述性横断面研究检查了加拿大移民和长期居民HBV和hcv相关住院、住院时间、合并症和后遗症的分布。以85%的关联率，5,854,949名移民被纳入研究。计算移民导致的HBV和hcv相关住院的比例。结果:按出生国风险水平划分，新近移民中22%的hbv相关医院事件和20%的HCV相关医院事件来自高危国家。从比例上看，移民比长期居民有更少的合并症。在两组中，与医院相关的前两种后遗症是肝硬化和腹水，以及肝癌。虽然移民占加拿大人口的16%，但他们发生了37%的hbv相关住院和9%的hcv相关住院，相对于人口份额，肝炎相关住院的比率分别为2.3(95%置信区间[CI]: 2.2至2.5)和0.5 (95% CI: 0.5至0.6)。这些比率在老年人中更高，分别为4.4 (95% CI: 3.9至4.9)和2.3 (95% CI: 1.9至2.6)。解释:移民在加拿大可能需要因肝炎住院治疗，尤其是乙型肝炎。这些结果可能为加拿大移民背景下的HBV或HCV健康筛查提供信息。

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Hospitalization related to chronic hepatitis B and C in recent immigrants in Canada: An immigration administrative data-linked, population-based cohort study.

Background: Canadian immigrants from countries where the hepatitis B virus (HBV) and hepatitis C virus (HCV) are endemic may be at higher risk of liver-related disease than Canadian-born residents. This study compared HBV- and HCV-related hospitalizations in Canadian immigrants (arriving from 1980 to 2013) and long-term residents (Canadian-born population and pre-1980 immigrants) and aimed to describe the burden of disease in both groups.

Methods: Based on the 2004/2005-to-2013/2014 hospital Discharge Abstract Database linked to the 1980-to-2013 Longitudinal Immigration Database, this descriptive cross-sectional study examined the distribution of HBV- and HCV-related hospitalizations, lengths of stay, comorbidities, and sequelae incurred by immigrants and long-term residents in Canada. With a linkage rate of 85%, 5,854,949 immigrants were included in the study. Proportions of HBV- and HCV-related hospitalizations attributable to immigrants were calculated.

Results: By birth country risk level, 22% of HBV-related hospital events among recent immigrants, and 20% of those related to HCV, were among people from high-risk countries. Proportionally, fewer immigrants had comorbidities than long-term residents. The top two hospital-related sequelae in both groups were cirrhosis and ascites, and liver cancer. While immigrants made up 16% of the Canadian population, they incurred 37% of HBV-related hospitalizations and 9% of HCV-related hospitalizations, giving ratios of hepatitis-related hospitalizations relative to the population share of 2.3 (95% confidence interval [CI]: 2.2 to 2.5) and 0.5 (95% CI: 0.5 to 0.6) respectively. These ratios were higher among seniors, at 4.4 (95% CI: 3.9 to 4.9) and 2.3 (95% CI: 1.9 to 2.6), respectively.

Interpretation: Immigrants can require hospitalization for hepatitis in Canada, especially for HBV. These results may inform health screening for HBV or HCV in the Canadian immigration context.

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来源期刊

Health Reports PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

7.30

自引率

4.00%

发文量

期刊介绍： Health Reports publishes original research on diverse topics related to understanding and improving the health of populations and the delivery of health care. We publish studies based on analyses of Canadian national/provincial representative surveys or Canadian national/provincial administrative databases, as well as results of international comparative health research. Health Reports encourages the sharing of methodological information among those engaged in the analysis of health surveys or administrative databases. Use of the most current data available is advised for all submissions.