皮肤抗原呈递细胞上的腺病毒受体

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2022-07-30 DOI:10.1111/boc.202200043
Elina Gerber-Tichet Dienst, Eric J. Kremer
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引用次数: 1

摘要

皮肤是人体最大的器官,是抵御许多病原体的第一道物理和免疫防线的一部分。了解皮肤抗原提呈细胞(apc)如何对病毒或基于病毒的疫苗作出反应,对于开发抗病毒药物以及高效和安全的疫苗至关重要。在这里,我们讨论常驻和招募皮肤apc参与腺病毒的方式和对先天免疫反应的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Adenovirus receptors on antigen-presenting cells of the skin

Skin, the largest human organ, is part of the first line of physical and immunological defense against many pathogens. Understanding how skin antigen-presenting cells (APCs) respond to viruses or virus-based vaccines is crucial to develop antiviral pharmaceutics, and efficient and safe vaccines. Here, we discuss the way resident and recruited skin APCs engage adenoviruses and the impact on innate immune responses.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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