子宫动脉栓塞联合超声引导下扩张刮除术治疗剖宫产瘢痕妊娠的疗效及5 - 8年随访研究

Zhuxin Gu , Pengfei Jia , Ziyang Gao , Weiwei Gu , Hui Zhao , Suming Zhao
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引用次数: 2

摘要

目的评价超声子宫动脉栓塞术(UAE)联合子宫扩张刮除术(D&C)治疗剖宫产瘢痕妊娠(CSP)的疗效和安全性,并评价其对卵巢和生殖功能的影响。方法回顾性分析2011年1月~ 2015年12月子宫CSP患者54例。采用超声联合UAE联合D&C治疗CSP,随访5-8年。分析患者的病历、病史、临床表现、疗程及治疗结果。结果54例患者初治无严重并发症。β-人绒毛膜促性腺激素(β-hCG)正常化需要36.11±10.73天(范围,25-84天),住院时间6.6±1.5天(范围,4-10天),总失血量18.48±8.41 mL(范围,5-33 mL)。术后33.48±8.71 d(范围:26 ~ 70 d)月经恢复正常。UAE联合超声D&C治疗子宫CSP后5 ~ 8年随访,32例(59.3%)患者月经量较术前下降。与前处理相比,月经周期延长2例(3.7%),缩短10例(18.5%),不规则1例(1.9%),不变39例(72.2%)。三名患者自然受孕并成功生下健康的孩子。7例(12.96%)意外自然妊娠患者选择人工流产,性生活无明显改变。结论uae联合超声D&C治疗子宫CSP安全有效,不影响40岁高龄患者的生育能力。然而,一些患者的月经量可能会减少。
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Uterine artery embolization combined with ultrasound-guided dilation and curettage for the treatment of cesarean scar pregnancy: Efficacy and 5–8-year follow-up study

Objective

To evaluate the efficacy and safety of uterine artery embolization (UAE) combined with dilation and curettage (D&C) using ultrasound as a treatment for cesarean scar pregnancy (CSP) and assess its effect on ovarian and reproductive function.

Methods

A total of 54 patients with uterine CSP between January 2011 and December 2015 were included in this retrospective study. The patients were treated with UAE combined with D&C using ultrasound for the treatment of CSP and followed up for 5–8 years. Their medical records, medical histories, clinical manifestations, treatment courses, and treatment results were analyzed.

Results

The 54 patients were initially treated without severe complications. β-Human chorionic gonadotropin (β-hCG) normalization took 36.11 ​± ​10.73 days (range, 25–84 days), length of hospitalization was 6.6 ​± ​1.5 days (range, 4–10 days), and total blood loss was 18.48 ​± ​8.41 ​mL (range, 5–33 ​mL). All patients resumed normal menstruation after 33.48 ​± ​8.71 days (range, 26–70 days). At the 5–8-year follow-up after UAE combined with D&C by ultrasound for the treatment of uterine CSP, the menstrual volume in 32 (59.3%) patients decreased versus before the operation. Compared with pretreatment, the menstrual cycle was prolonged in two (3.7%) cases, shortened in 10 (18.5%) cases, irregular in one (1.9%) case, and unchanged in 39 (72.2%) cases. Three patients conceived naturally and successfully gave birth to healthy children. Seven (12.96%) patients with accidental natural pregnancies chose induced abortion with no significant change in their sex lives.

Conclusion

UAE combined with D&C using ultrasound for the treatment of uterine CSP is safe and effective and may not affect the fertility of patients aged <40 years. However, menstrual volume may be reduced in some patients.

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来源期刊
Journal of Interventional Medicine
Journal of Interventional Medicine Medicine-General Medicine
CiteScore
1.30
自引率
0.00%
发文量
32
审稿时长
68 days
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