高度近视眼的眼前节生物测定。

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2023-01-01 Epub Date: 2022-08-04 DOI:10.1159/000526280

Mu Li, Zhaoxia Luo, Xiaoqin Yan, Zhiqi Chen

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引用次数: 0

摘要

简介：本研究旨在调查和比较高度近视组和对照组的眼前节生物测量指标：本研究旨在调查和比较高度近视组和对照组的眼前节生物测量：纳入 34 名高度近视患者的 34 只眼睛和 42 名对照组受试者的 42 只眼睛。使用扫源光学相干断层扫描测量了施莱姆管（SC）面积、小梁网（TM）厚度和长度、巩膜距（SS）长度和前巩膜厚度（AST）。还估算了 SC 面积、TM 厚度、TM 长度、SS 长度和 AST 之间的关联：高度近视组和对照组的 SC 面积、TM 厚度和 SS 长度与 AST0（距 SS 0 毫米处的 AST）显著相关。AST0（702.61 ± 78.05 vs. 729.12 ± 95.87 μm，p = 0.085）和 SS 长度（206.25 ± 52.25 vs. 212.09 ± 51.86 μm，p = 0.556）在高度近视组和对照组之间无明显差异，而 SC 面积（6622.68 ± 1,130.06 vs. 6,105.85 ± 1,297.84 μm2，p = 0.015）明显大于对照组，高度近视组的TM厚度（96.15 ± 34.40 vs. 107.93 ± 29.97 μm，p = 0.048）明显薄于对照组：结论：SC 面积和 TM 厚度与 AST0 显著相关，而 AST0 和 SS 长度在高度近视组和对照组之间无显著差异。高度近视眼SC和TM尺寸的变化可能是由AST0和SS长度以外的因素引起的。

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The Anterior Segment Biometrics in High Myopia Eyes.

Introduction: The aim of this study was to investigate and compare the anterior segment biometrics in high myopia and control groups.

Methods: Thirty-four eyes of 34 high myopia patients and 42 eyes of 42 control subjects were included. Schlemm's canal (SC) area, trabecular meshwork (TM) thickness and length, scleral spur (SS) length, and anterior scleral thickness (AST) were measured using swept-source optical coherence tomography. Associations between SC area, TM thickness, TM length, SS length, and AST were also estimated.

Results: SC area, TM thickness, and SS length were significantly associated with AST0 (AST at 0 mm from SS) in both high myopia and control groups. AST0 (702.61 ± 78.05 vs. 729.12 ± 95.87 μm, p = 0.085) and SS length (206.25 ± 52.25 vs. 212.09 ± 51.86 μm, p = 0.556) were not significantly different between high myopia and control groups, whereas SC area (6,622.68 ± 1,130.06 vs. 6,105.85 ± 1,297.84 μm2, p = 0.015) was significantly greater and TM thickness (96.15 ± 34.40 vs. 107.93 ± 29.97 μm, p = 0.048) was significantly thinner in high myopia group than in control group.

Conclusion: SC area and TM thickness were significantly associated with AST0, while AST0 and SS length were not significantly different between high myopia and control groups. The changes in SC and TM dimensions in high myopia eyes might be caused by factors other than AST0 and SS length.

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.