视网膜母细胞瘤的治疗选择和治疗失败。

Q1 Medicine Neurosignals Pub Date : 2022-11-11 DOI:10.33594/000000585

Argyrios Chronopoulos, Neele Babst, Christian Schiemenz, James S Schutz, Ludwig M Heindl, Mahdy Ranjbar, Vinodh Kakkassery

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引用次数: 3

摘要

视网膜母细胞瘤(RB)的管理在过去的三十年中不断发展。现代RB治疗的目标首先是保护生命和预防转移性疾病，然后是保存全球和有用的视力。随着现代治疗方案和早期疾病检测的成功率可以达到100%的无病全球和眼睛保护。晚期病例的治疗仍然复杂，需要积极的化疗或/和外部放射治疗。治疗方案非常多样化，依赖于当地资源，因此成功率是可变的。在这里，我们回顾了目前的治疗方案和失败率基于PubMed搜索关键词视网膜母细胞瘤，视网膜母细胞瘤种子，视网膜母细胞瘤治疗，去核。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Narrative Review - Therapy Options and Therapy Failure in Retinoblastoma.

Retinoblastoma (RB) management has evolved over the last three decades. Goals of modern RB treatment are first to protect life and prevent metastatic disease, then preservation of the globe and useful vision. With modern treatment protocols and early disease detection success rates can reach up to 100% of disease-free-globe and eye preservation. Treatment of advanced cases remains complex, requiring aggressive chemotherapy or/and external beam radiation. Treatment protocols are extremely diverse and dependent on local resources thus success rates are variable. Here we review narratively current treatment protocols and failure rates based on a PubMed search using keywords of retinoblastoma, retinoblastoma seed, retinoblastoma treatment, enucleation.

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来源期刊

Neurosignals 医学-神经科学

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Neurosignals is an international journal dedicated to publishing original articles and reviews in the field of neuronal communication. Novel findings related to signaling molecules, channels and transporters, pathways and networks that are associated with development and function of the nervous system are welcome. The scope of the journal includes genetics, molecular biology, bioinformatics, (patho)physiology, (patho)biochemistry, pharmacology & toxicology, imaging and clinical neurology & psychiatry. Reported observations should significantly advance our understanding of neuronal signaling in health & disease and be presented in a format applicable to an interdisciplinary readership.