土耳其老年人群25-羟基维生素D (25-OHD)水平:一项全国性研究

IF 2 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Medical Biochemistry Pub Date : 2022-10-15 DOI:10.5937/jomb0-36921
Murat Çağlayan, Cigdem Sonmez, Mehmet Senes, Ataman Gonel, Ozlem Gulbahar, Nurbanu Bursa, Derun Taner, Osman Celik, Fidanci Ali Aykut, Ulgu Mustafa Mahir, Abdulvahit Sozuer, Naim Ata, Suayip Birinci
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引用次数: 0

摘要

背景:在世界范围内,25-羟基维生素D (25-OHD)缺乏是与老年人群中许多慢性疾病相关的主要健康问题。在这项研究之前,没有关于土耳其65岁以上人群25-OHD水平的数据。本研究的目的是评估土耳其65岁以上人群25-OHD水平及其季节性变化。方法:本研究包括2016年、2017年和2018年对65岁以上的土耳其人口进行的维生素D测量。定义了研究人群的年龄、性别和季节平均数据。研究数据来自卫生部的数据库,并使用Kolmogorov-Smirnov检验来评估数据的分布。由于数据是非参数的,因此计算了所有类别的中位数和四分位数范围(IQRs)。结果:在这项研究中,从老年人身上采集的维生素D测量量在2016年为305329,2017年为576452,2018年为752837。该人群25-OHD水平的中位数和IQR分别为2016年16 μg/L (IQR 7.45-24.55 μg/L)、2017年16.1 μg/L (IQR 7.8-24.4 μg/L)和2018年16.4 μg/L (IQR 8.95-23.85 μ L)。结论:虽然在土耳其,老年男性的25-OHD水平在季节性阳光照射期间趋于增加,但在老年女性中观察到这种变异性。这表明,老年女性往往过着久坐不动的生活,日照不足。总体而言,65岁以上人群25-OHD的中位数呈逐年下降趋势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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25-hydroxyvitamin D (25-OHD) levels in Turkish geriatric population: A nationwide study.
Background Across the world, 25-hydroxyvitamin D (25-OHD) deficiency is a major health problem associated with many chronic diseases in the geriatric population. Prior to this study, there were no data regarding 25-OHD levels among individuals over the age of 65 in Turkey. The aim of this study was to assess 25-OHD levels and seasonal variations in these values among people over the age of 65 in Turkey. Methods This study included vitamin D measurements taken in 2016, 2017, and 2018 from the Turkish population over the age of 65. The age, gender, and seasonal average data of the study population were defined. The study data were obtained from the database of the Ministry of Health, and a Kolmogorov-Smirnov test was used to assess the distribution of the data. Medians and interquartile ranges (IQRs) were calculated for all categories, as the data were nonparametric. Results The number of vitamin D measurements taken from the geriatric individuals included in this study was 305,329 for 2016, 576,452 for 2017, and 752,837 for 2018. The medians and IQRs of the 25-OHD levels in this population were 16 μg/L (IQR 7.45-24.55 μg/L) for 2016, 16.1 μg/L (IQR 7.8-24.4 μg/L) for 2017, and 16.4 μg/L (IQR 8.95-23.85 μg/L) for 2018. Conclusions While the 25-OHD levels of older men tended to increase during the period of seasonal sunlight in Turkey, this variability was observed in elderly women. This suggests that older women tend to live more sedentary lives and have insufficient sun exposure. Overall, the median 25-OHD levels of individuals over the age of 65 tended to decrease each year.
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来源期刊
Journal of Medical Biochemistry
Journal of Medical Biochemistry BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
3.00
自引率
12.00%
发文量
60
审稿时长
>12 weeks
期刊介绍: The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly. The Journal publishes original scientific and specialized articles on all aspects of clinical and medical biochemistry, molecular medicine, clinical hematology and coagulation, clinical immunology and autoimmunity, clinical microbiology, virology, clinical genomics and molecular biology, genetic epidemiology, drug measurement, evaluation of diagnostic markers, new reagents and laboratory equipment, reference materials and methods, reference values, laboratory organization, automation, quality control, clinical metrology, all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.
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