寻常型天疱疮患者饮食多样性评分与心血管危险因素的相关性:一项横断面研究

Clinical nutrition research Pub Date : 2022-10-24 eCollection Date: 2022-10-01 DOI:10.7762/cnr.2022.11.4.289
Atefeh Seifollahi, Mahboubeh Rezaei Fazl, Leila Setayesh, Mohammad Hassan Javanbakht, Maryam Daneshpazhooh, Sakineh Shab-Bidar, Mehdi Yaseri
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摘要

本研究旨在评估该人群饮食多样性评分(DDS)与心血管危险因素之间的关系。在这项横断面研究中,187例年龄在18-65岁的寻常型天疱疮患者被纳入研究。采用24小时膳食回忆法评估DDS。根据标准方案评估人体测量和生化参数。多变量线性回归分析用于检测DDS与心血管危险因素之间的关联。研究对象的平均±标准差年龄和体重指数分别为(46.71±11.49岁)和(27.83±4.39 kg/m2)。我们的研究结果表明,DDS摄入量的增加与蔬菜(p = 0.001)、乳制品(p < 0.001)、谷物(p = 0.002)、红肉和加工肉(p < 0.001)、糖果和甜点(p < 0.001)的摄入量增加有关。在控制混杂变量后,结果显示DDS与高密度脂蛋白胆固醇(HDL-C, β = 1.87, 95%可信区间[CI], 0.30 ~ 3.45, p = 0.02)和总胆固醇(TC)水平(β = 6.41, 95% CI, 1.62 ~ 11.03, p = 0.02) (β = 1.75, 95% CI, 0.20 ~ 3.30, p = 0.02)呈正相关。然而,DDS与肥胖患病率和葡萄糖稳态之间没有关联。本横断面研究结果显示,DDS可能与HDL-C和TC升高有关。然而,需要进一步的前瞻性研究来证明这些发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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The Association Between Dietary Diversity Score and Cardiovascular Risk Factors Among Patients With Pemphigus Vulgaris: A Cross Sectional Study.

This study was conducted to evaluate the associations between dietary diversity score (DDS) and cardiovascular risk factors in this population. In this cross-sectional study, 187 patients, aged 18-65 years with pemphigus vulgaris were included. DDS was assessed by a 24-hour dietary recall method. Anthropometric measures and biochemical parameters assessed according to standard protocols. Multivariate linear regression analyses used for detecting any associations between DDS and cardiovascular risk factors. The mean ± standard deviation age and body mass index of studied participants were (46.71 ± 11.49 years) and (27.83 ± 4.39 kg/m2) respectively. Our findings showed that a higher DDS intake was related with higher consumption of vegetables (p = 0.001), dairy products (p < 0.001), cereals (p = 0.002), red and processed meat (p < 0.001), sweets and desserts (p < 0.001). After controlling for confounding variables, the results showed positive associations between DDS and high-density lipoprotein cholesterol (HDL-C, β = 1.87, 95% confidence interval [CI], 0.30-3.45, p = 0.02) and total cholesterol (TC) levels (β = 6.41, 95% CI, 1.62-11.03, p = 0.02) (β = 1.75, 95% CI, 0.20-3.30, p = 0.02). However, there were no associations between DDS and prevalence of obesity and glucose homeostasis. The results of this cross-sectional study showed that DDS might be associated with increased HDL-C and TC. However, further prospective studies are needed to prove these findings.

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