术前房颤预示着LVAD植入后更糟糕的结果。

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular and Thoracic Research Pub Date : 2022-01-01 Epub Date: 2022-08-30 DOI:10.34172/jcvtr.2022.29
Moritz Benjamin Immohr, Yukiharu Sugimura, Esma Yilmaz, Hug Aubin, Udo Boeken, Payam Akhyari, Artur Lichtenberg, Hannan Dalyanoglu
{"title":"术前房颤预示着LVAD植入后更糟糕的结果。","authors":"Moritz Benjamin Immohr,&nbsp;Yukiharu Sugimura,&nbsp;Esma Yilmaz,&nbsp;Hug Aubin,&nbsp;Udo Boeken,&nbsp;Payam Akhyari,&nbsp;Artur Lichtenberg,&nbsp;Hannan Dalyanoglu","doi":"10.34172/jcvtr.2022.29","DOIUrl":null,"url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Left ventricular assist device (LVAD) implantation is a common therapy for end-stage heart failure. Heart failure patients often present with atrial fibrillation (AF). The purpose of this study was to evaluate the influence of preoperative AF as well as vascular complications on outcome in LVAD patients. <b><i>Methods:</i></b> Between 01/2010 and 12/2017, 168 patients (141 male) with end-stage heart failure underwent LVAD implantation at a single center. Patient outcome was retrospectively studied by using the Kaplan-Meier method for analyzing crude survival as well as Cox regression for analyzing risk factors. <b><i>Results:</i></b> Sixty-two patients suffered from preoperative atrial fibrillation at LVAD implantation. Mean age was 56.8±11.9 years (range: 22-79) and 141 (84%) were male. Postoperative vascular or visceral surgical management due to malperfusion was needed in 27 patients (16.1%) and did not correlate with postoperative mortality (<i>P</i>=0.121, HR=1.587, CI=0.885-2.845). Patients with preoperative AF had a worse outcome in the Kaplan-Meier analysis (<i>P</i>=0.069). In contrast, cox regression showed that postoperative AF could not to be considered to be an independent predictor of mortality in this study group. <b><i>Conclusion:</i></b> Our data suggest that preoperative AF may be a potential predictor of mortality and impaired long-term outcome in LVAD patients. In contrast, preoperative ECLS and vascular or visceral surgery after LVAD implantation did not represent limiting factors with regard to mortality after LVAD implantation.</p>","PeriodicalId":15207,"journal":{"name":"Journal of Cardiovascular and Thoracic Research","volume":"14 3","pages":"166-171"},"PeriodicalIF":1.2000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617056/pdf/","citationCount":"0","resultStr":"{\"title\":\"Preoperative atrial fibrillation predicts worse outcomes after LVAD implantation.\",\"authors\":\"Moritz Benjamin Immohr,&nbsp;Yukiharu Sugimura,&nbsp;Esma Yilmaz,&nbsp;Hug Aubin,&nbsp;Udo Boeken,&nbsp;Payam Akhyari,&nbsp;Artur Lichtenberg,&nbsp;Hannan Dalyanoglu\",\"doi\":\"10.34172/jcvtr.2022.29\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Introduction:</i></b> Left ventricular assist device (LVAD) implantation is a common therapy for end-stage heart failure. Heart failure patients often present with atrial fibrillation (AF). The purpose of this study was to evaluate the influence of preoperative AF as well as vascular complications on outcome in LVAD patients. <b><i>Methods:</i></b> Between 01/2010 and 12/2017, 168 patients (141 male) with end-stage heart failure underwent LVAD implantation at a single center. Patient outcome was retrospectively studied by using the Kaplan-Meier method for analyzing crude survival as well as Cox regression for analyzing risk factors. <b><i>Results:</i></b> Sixty-two patients suffered from preoperative atrial fibrillation at LVAD implantation. Mean age was 56.8±11.9 years (range: 22-79) and 141 (84%) were male. Postoperative vascular or visceral surgical management due to malperfusion was needed in 27 patients (16.1%) and did not correlate with postoperative mortality (<i>P</i>=0.121, HR=1.587, CI=0.885-2.845). Patients with preoperative AF had a worse outcome in the Kaplan-Meier analysis (<i>P</i>=0.069). In contrast, cox regression showed that postoperative AF could not to be considered to be an independent predictor of mortality in this study group. <b><i>Conclusion:</i></b> Our data suggest that preoperative AF may be a potential predictor of mortality and impaired long-term outcome in LVAD patients. In contrast, preoperative ECLS and vascular or visceral surgery after LVAD implantation did not represent limiting factors with regard to mortality after LVAD implantation.</p>\",\"PeriodicalId\":15207,\"journal\":{\"name\":\"Journal of Cardiovascular and Thoracic Research\",\"volume\":\"14 3\",\"pages\":\"166-171\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617056/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cardiovascular and Thoracic Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34172/jcvtr.2022.29\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/8/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiovascular and Thoracic Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/jcvtr.2022.29","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/8/30 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

摘要

左心室辅助装置(LVAD)植入术是终末期心力衰竭的常用治疗方法。心力衰竭患者常伴有心房颤动(AF)。本研究的目的是评估术前房颤及血管并发症对LVAD患者预后的影响。方法:2010年1月至2017年12月,168例终末期心力衰竭患者(141例男性)在同一中心接受LVAD植入。回顾性研究患者预后,采用Kaplan-Meier法分析粗生存率,Cox回归法分析危险因素。结果:62例患者在LVAD植入术前出现房颤。平均年龄56.8±11.9岁(22 ~ 79岁),男性141例(84%)。27例(16.1%)患者因灌注不良需要进行术后血管或内脏手术处理,且与术后死亡率无关(P=0.121, HR=1.587, CI=0.885-2.845)。Kaplan-Meier分析显示,术前房颤患者预后较差(P=0.069)。相比之下,cox回归显示,术后房颤不能被认为是本研究组死亡率的独立预测因子。结论:我们的数据表明,术前房颤可能是LVAD患者死亡率和远期预后受损的潜在预测因素。相比之下,术前ECLS和LVAD植入后的血管或内脏手术并不是LVAD植入后死亡率的限制因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Preoperative atrial fibrillation predicts worse outcomes after LVAD implantation.

Introduction: Left ventricular assist device (LVAD) implantation is a common therapy for end-stage heart failure. Heart failure patients often present with atrial fibrillation (AF). The purpose of this study was to evaluate the influence of preoperative AF as well as vascular complications on outcome in LVAD patients. Methods: Between 01/2010 and 12/2017, 168 patients (141 male) with end-stage heart failure underwent LVAD implantation at a single center. Patient outcome was retrospectively studied by using the Kaplan-Meier method for analyzing crude survival as well as Cox regression for analyzing risk factors. Results: Sixty-two patients suffered from preoperative atrial fibrillation at LVAD implantation. Mean age was 56.8±11.9 years (range: 22-79) and 141 (84%) were male. Postoperative vascular or visceral surgical management due to malperfusion was needed in 27 patients (16.1%) and did not correlate with postoperative mortality (P=0.121, HR=1.587, CI=0.885-2.845). Patients with preoperative AF had a worse outcome in the Kaplan-Meier analysis (P=0.069). In contrast, cox regression showed that postoperative AF could not to be considered to be an independent predictor of mortality in this study group. Conclusion: Our data suggest that preoperative AF may be a potential predictor of mortality and impaired long-term outcome in LVAD patients. In contrast, preoperative ECLS and vascular or visceral surgery after LVAD implantation did not represent limiting factors with regard to mortality after LVAD implantation.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Cardiovascular and Thoracic Research
Journal of Cardiovascular and Thoracic Research CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.00
自引率
0.00%
发文量
22
审稿时长
7 weeks
期刊最新文献
Evaluating the relationship between lactate levels during coronary artery bypass graft surgery and postoperative renal dysfunction. Genetic association of FTO gene polymorphisms with obesity and its related phenotypes: A case-control study. Risk estimation of cardiovascular diseases using the World Health Organization/International Society of Hypertension risk prediction charts in the Azar cohort population: Cross-sectional study. The role of probiotics on microvascular complications of type-2 diabetes: Nephropathy and retinopathy. Walking or breathing: comparing the 6-minute walking distance test to the pulmonary function test for lung resection candidates.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1