{"title":"用人二倍体细胞株wi-38制备的狂犬病疫苗成功免疫灵长类动物。","authors":"T J WIKTOR, H KOPROWSKI","doi":"10.3181/00379727-118-30048","DOIUrl":null,"url":null,"abstract":"Summary The antigenicity of 2 strains of rabies virus (Flury HEP and Pitman-Moore) propagated in a Human Diploid Cell Strain and used as live and inactivated vaccine was studied in Rhesus monkeys. It was found that these strains were much more antigenic than the same strains of virus propagated in embryonated avian egg before adaptation to tissue culture. The use of this tissue culture vaccine in man should be contemplated.","PeriodicalId":20675,"journal":{"name":"Proceedings of the Society for Experimental Biology and Medicine","volume":" ","pages":"1069-73"},"PeriodicalIF":0.0000,"publicationDate":"1965-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3181/00379727-118-30048","citationCount":"46","resultStr":"{\"title\":\"SUCCESSFUL IMMUNIZATION OF PRIMATES WITH RABIES VACCINE PREPARED IN HUMAN DIPLOID CELL STRAIN WI-38.\",\"authors\":\"T J WIKTOR, H KOPROWSKI\",\"doi\":\"10.3181/00379727-118-30048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary The antigenicity of 2 strains of rabies virus (Flury HEP and Pitman-Moore) propagated in a Human Diploid Cell Strain and used as live and inactivated vaccine was studied in Rhesus monkeys. It was found that these strains were much more antigenic than the same strains of virus propagated in embryonated avian egg before adaptation to tissue culture. The use of this tissue culture vaccine in man should be contemplated.\",\"PeriodicalId\":20675,\"journal\":{\"name\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"1069-73\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1965-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3181/00379727-118-30048\",\"citationCount\":\"46\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3181/00379727-118-30048\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Society for Experimental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3181/00379727-118-30048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SUCCESSFUL IMMUNIZATION OF PRIMATES WITH RABIES VACCINE PREPARED IN HUMAN DIPLOID CELL STRAIN WI-38.
Summary The antigenicity of 2 strains of rabies virus (Flury HEP and Pitman-Moore) propagated in a Human Diploid Cell Strain and used as live and inactivated vaccine was studied in Rhesus monkeys. It was found that these strains were much more antigenic than the same strains of virus propagated in embryonated avian egg before adaptation to tissue culture. The use of this tissue culture vaccine in man should be contemplated.
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