[Collagen matrix mesh implants (Veritas) in the surgical therapy of cystocele].

Collagen Matrix Mesh Implants (Veritas) in the Surgical Therapy of Cystocele Introduction: Grade 3 and 4 cystocele repair using Veritas TM collagen matrix implants was carried out in a preliminary study to assess the feasibility and efficacy of the Veritas collagen matrix implant for the treatment of recurrent cystocele. Material and Methods: Eighteen patients who underwent anterior vaginal wall repair via a vaginal approach with Veritas bovine collagen matrix (Synovis, St. Paul, Minn., USA) were retrospectively evaluated. All wall repairs were reinforced with Veritas collagen matrix. The women were postmenopausal and used vaginal estrogen for at least 2 weeks preoperatively. Healing was assessed by prolapse recurrence and the presence of infection, granulation tissue and suture materials in the vagina postoperatively. Results: None of the 18 patients developed a postoperative vaginal infection, and none had vaginal erosion of the material. No patient had tissue disruption at the suture lines. The followup examinations were immediately after surgery and after 6, 12 and 18 months (median 15 months). There were no vessel or bladder injuries. One hematoma was noted but no other postoperative complication. One nonsymptomatic recurrent cystocele was described. Conclusion: The Veritas collagen matrix implant does not appear to impede healing in vaginal urogynecological surgery. These preliminary results suggest that bovine collagen implantation is a safe and effective treatment for anterior vaginal wall prolapse. Further studies with longer follow-ups are needed.