胰腺癌患者躁狂发作1例报告。

IF 2.1 3区 医学 Q3 PHARMACOLOGY & PHARMACY International Clinical Psychopharmacology Pub Date : 2024-09-01 Epub Date: 2023-09-20 DOI:10.1097/YIC.0000000000000505
Juan I Mena, Helena Andreu, Anna Giménez-Palomo, Laura Bueno, Eduard Cesari, Óscar De Juan, Iñaki Ochandiano, Luis Olivier, Sergi Salmeron, Eduard Vieta, Isabella Pacchiarotti
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引用次数: 0

摘要

精神病合并症在癌症患者中很常见,强调需要综合护理。虽然对癌症患者的抑郁症状进行了研究,但对躁狂症状的关注有限。本病例报告旨在通过描述一例胰腺癌癌症IV期患者突发躁狂发作的病例,为了解胰腺癌癌症精神病合并症做出贡献。该患者是一名61岁的男性,患有癌症IV期,在急诊室出现了突然的行为变化,暗示躁狂发作2 经过数周的进化。在过去的9年中,患者一直在接受化疗和短期的3天皮质类固醇治疗 但已经停止了20个月的治疗 事件开始的几天。排除了急性器质性病因。患者被送入精神科,在那里扩大了器质性筛查,并开始使用抗精神病药物和情绪稳定剂进行治疗,随后症状在2 周。该病例显示躁狂发作是癌症罕见的精神并发症。在所审查的文献中,还观察到其他四个类似的案例。需要进一步的研究来阐明潜在的病理生理学并探索可能的治疗策略。
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Manic episode in a patient with pancreatic adenocarcinoma: a case report.

Psychiatric comorbidity is common in cancer patients, emphasizing the need for comprehensive care. While depressive symptoms in pancreatic cancer have been studied, there is limited attention given to manic symptoms. This case report aims to contribute to the knowledge of pancreatic cancer psychiatric comorbidities by describing a case of a patient with stage IV pancreatic cancer who presented a sudden onset manic episode. The patient, a 61-year-old male with stage IV pancreatic cancer, presented at the Emergency Room with abrupt behavioural changes suggestive of a manic episode of 2 weeks of evolution. The patient had been undergoing chemotherapy and short 3-day cycles of corticosteroids for the past 9 months but had been off this treatment for 20 days when the episode began. Acute organic causes were ruled out. The patient was admitted to the psychiatric unit, where organic screening was expanded and treatment with antipsychotics and a mood stabiliser was initiated with subsequent remission of symptoms after 2 weeks. This case shows a manic episode as a rare psychiatric complication in pancreatic cancer. In the literature reviewed, four other similar cases have been observed. Further research is needed to elucidate the underlying pathophysiology and explore possible treatment strategies.

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来源期刊
CiteScore
4.40
自引率
23.10%
发文量
97
审稿时长
>12 weeks
期刊介绍: International Clinical Psychopharmacology provides an essential link between research and clinical practice throughout psychopharmacology. It reports on studies in human subjects, both healthy volunteers and patients, which relate the effects of drugs on psychological processes. A major objective of the journal is to publish fully refereed papers which throw light on the ways in which the study of psychotropic drugs can increase our understanding of psychopharmacology. To this end the journal publishes results of early Phase I and II studies, as well as those of controlled clinical trials of psychotropic drugs in Phase II and IV. Other topics covered include the epidemiology of psychotropic drug prescribing and drug taking, the sociology of psychotropic drugs including compliance, and research into the safety and adverse effects of these compounds.
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