减肥手术的额外准备计划:一项大型队列研究的两年结果。

IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Obesity Science & Practice Pub Date : 2023-05-10 eCollection Date: 2023-10-01 DOI:10.1002/osp4.677
Yentl Lodewijks, Misha Luyer, Gust van Montfort, Jean-Paul de Zoete, Frans Smulders, Simon Nienhuijs
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引用次数: 0

摘要

背景:建议对减肥手术候选人进行多学科筛查,一些中心提供额外的准备计划(APP)来优化患者的术前治疗。目的:比较原发性减肥手术后2年APP患者与标准护理的术后体重减轻和肥胖相关合并症的解决情况。方法:对2017年9月至2019年3月期间接受原发性Roux-en-Y胃旁路术和袖状胃切除术的患者进行回顾性队列研究。在患者接受APP治疗的前12个月,2018年9月后,APP不再是减肥轨迹的一部分。建立了多变量线性回归模型。结果:在384名接受APP建议的患者中,有50人失去了随访。总共有192人(57%)接受了APP,142人(43%)接受了标准护理。2年后总体重减轻的百分比有显著差异,APP组为28.8%,标准组为32%(p=0.001)。在多变量分析中,接受胃旁路术、基线体重指数较高和女性的患者2年后体重减轻增加。APP可预测术后体重减轻。与标准组(61.9%,p=0.028)相比,准备组(84.1%的病例)的糖尿病病情明显缓解。对于合并症,APP组的糖尿病缓解率更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Additional preparation program for bariatric surgery: Two-year results of a large cohort study.

Background: Multidisciplinary screening of bariatric surgery candidates is recommended, and some centers provide an additional preparation program (APP) to optimize patients preoperatively.

Objective: To compare patients with APP to standard care 2 years after primary bariatric surgery regarding postoperative weight loss and resolution of obesity-related comorbidities.

Methods: A retrospective cohort study was conducted for patients undergoing primary Roux-en-Y gastric bypass and sleeve gastrectomy between September 2017 and March 2019. The first 12 months patients received an APP, after September 2018, the APP was no longer part of the weight loss trajectory. A multivariable linear regression model was built.

Results: Of the 384 patients receiving an APP advice, 50 were lost to follow up. In total, 192 (57%) received the APP and 142 (43%) received standard care. Percentage total weight loss after 2 years was significantly different, 28.8% for the APP group versus 32% for the standard group (p = 0.001). Postoperative weight loss after 2 years was increased in patients who had a gastric bypass, a higher baseline body mass index, and female gender in multivariable analysis. An APP was predictive for decreased postoperative weight. Diabetes mellitus was in remission significantly more often in the preparation group (84.1% of the cases) compared with the standard group (61.9%, p = 0.028).

Conclusion: A weight loss trajectory is at least as effective without additional preparation in terms of 2 years postoperative %TWL for primary gastric bypass and sleeve procedures. For comorbidities, diabetes mellitus was in remission more often in the APP group.

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来源期刊
Obesity Science & Practice
Obesity Science & Practice ENDOCRINOLOGY & METABOLISM-
CiteScore
4.20
自引率
4.50%
发文量
73
审稿时长
29 weeks
期刊最新文献
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