心房颤动导管消融术后空白期定义及早期复发意义的再思考。

IF 2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Current Opinion in Cardiology Pub Date : 2024-01-01 Epub Date: 2023-09-18 DOI:10.1097/HCO.0000000000001096
Songnan Wen, Yu Liao, Tejas S Khurana, Rong Bai
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引用次数: 0

摘要

综述目的:心房颤动导管消融术后,心房快速性心律失常(ERAT)在空白期(BP)早期复发并不罕见。目前的指南和共识声明建议对ERAT进行保守治疗。这篇综述总结了ERAT的最新研究、潜在机制和临床管理,并提出了对BP的定义和临床意义的重新思考。最近的发现:最近的研究表明,ERAT在BP的早期阶段(即前4 3个月周期的几周)不同于那些晚发的ERAT,后者与心房快速性心律失常的晚发复发密切相关。临床观察建议的最佳血压持续时间为21-58 天。使用抗心律失常药物和早期电复律是治疗ERAT的有效方法,而再次消融是一种合理的策略,尽管仍有争议。摘要:持续时间较短的BP的定义,即1 月而不是3 最新临床研究的观察结果支持了房颤消融术后数月的疗效。超过1个月的复发性房性快速性心律失常与晚期复发的风险较高相关,可能需要重复消融。需要重新审视ERAT管理指南建议,以改变临床实践。
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Reconsideration of the definition of blanking period and significance of early recurrences after catheter ablation of atrial fibrillation.

Purpose of review: Early recurrence of atrial tachyarrhythmia (ERAT) during blanking period (BP) is not uncommon after catheter ablation of AF. Current guidelines and consensus statements recommend conservative treatment of ERAT. This review summarized recent studies, underlying mechanism and clinical managements of ERAT, and proposed a reconsideration of the definition and clinical significance of BP.

Recent findings: Recent studies have shown that the entity of ERAT in the very early phase of BP (i.e., first 4 weeks of the 3-month period) is different from those ERATs occurring late which is strongly associated with the late recurrence of atrial tachyarrhythmia. The optimal BP duration suggested by clinical observation ranges from 21 to 58 days. Using antiarrhythmic drugs and early electrical cardioversion are the effective management for ERAT, whereas re-ablation is a reasonable strategy although remains controversial.

Summary: The definition of BP with a shorter duration, that is, 1 month instead of 3 months post AF ablation, is supported by the observations of latest clinical studies. Recurrent atrial tachyarrhythmia beyond the 1-month time frame is associated with higher risk of late recurrence and may warrant repeat ablation. A revisit to the guideline recommendation on management of ERAT is needed to change clinical practice.

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来源期刊
Current Opinion in Cardiology
Current Opinion in Cardiology 医学-心血管系统
CiteScore
4.20
自引率
4.30%
发文量
78
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Cardiology is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With fourteen disciplines published across the year – including arrhythmias, molecular genetics, HDL cholesterol and clinical trials – every issue also contains annotated reference detailing the merits of the most important papers.
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