【2010-2020年秘鲁心脏移植受者的流行病学特征】。

Gracia Del Carmen Polo Lecca, Franz Ronald Soplopuco Palacios, Walter Alberto Alarco León, Oscar Nelson Aguirre Zurita, Cristian Aguilar Carranza, Ruth Eneida Villarroel Villa, Tommy Leonel Prado Gómez, José Luis Tapia Leonardo, Miguel Ángel Lescano Alva, Víctor Justo Robles Velarde, Julio Alberto Morón Castro, Yulma Donayre Moquillaza, Teresa Colque Rojas, Luis Javier Palma Ortecho, David Germán Gálvez Caballero
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摘要

目的:评估2010-2020年美国国家心血管研究所心脏移植受者的流行病学、临床、外科、病理学特征和随访结果。材料和方法:通过回顾在国家转诊中心接受心脏移植的患者的病历,进行回顾性描述性研究,描述了患者的临床、外科、实验室、病理特征和长达10年的随访。结果:86名患者在10年内被移植,中位年龄为41岁(RIQ 28-56),主要是男性(66.3%)。心脏移植指征的三个主要原因是:扩张型心肌病(48.9%)、缺血性心脏病(17.4%),总缺血时间为160分钟(RIQ 129.7-233.5),1年、5年和10年生存率分别为84.8%、73.6%和65.7%。主要死因为非心脏性:传染性(39.1%)和不明原因(26%)。结论:近年来秘鲁心脏移植受者心力衰竭的主要病因是非缺血性扩张型心肌病。我们观察到,存活率与国际登记处的存活率相似;然而,由于感染原因和不明原因死亡的死亡率很高,这对移植后患者的管理提出了挑战。
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[Epidemiological characteristics of heart transplant recipients in Peru 2010-2020].

Objective: To evaluate the epidemiological, clinical, surgical, pathological characteristics and outcomes in the follow-up of heart transplant recipients at the National Cardiovascular Institute during 2010-2020.

Material and methods: A retrospective descriptive study was performed by reviewing the medical records of patients undergoing heart transplantation at a national referral center, describing the clinical, surgical, laboratory, pathology characteristics and survival of patients up to 10 years of follow-up.

Results: Eighty-six patients were transplanted in 10 years, the median age was 41 years (RIQ 28-56), being predominantly male (66.3%). The three leading causes of indication for heart transplantation were: dilated cardiomyopathy (48.9%), ischemic heart disease (17.4%), and myocarditis (6.9%). Total ischemia time was 160 minutes (RIQ 129.7-233.5). Survival at one, five, and ten years was 84.8%, 73.6%, and 65.7% respectively. The main cause of death was non-cardiac: infectious (39.1%) and of unknown origin (26%).

Conclusions: The main etiology of heart failure in heart transplant recipients in Peru in recent years was nonischemic dilated cardiomyopathy. We observed that the survival rate was similar to that of international registries; however, the rate of mortality due to infectious causes and death of unknown origin is high, which poses a challenge in the management of post-transplant patients.

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[Andersen-Tawil Syndrome, a differential of bidirectional ventricular tachycardia: a case report]. [Balloon atrioseptostomy under echocardiographic and fluoroscopic guide in patients with congenital heart diseases under 3 months in a national reference pediatric center]. [Frailty and adverse outcomes in patients over 65 years old with acute coronary syndrome in a hospital cohort in Medellin, Colombia]. [Hypertrophic cardiomyopathy with mid-ventricular phenotype and filamin C mutation, an uncommon case report]. [Neonatal screening for critical congenital heart diseases in Peru: an urgent call].
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