Legnica-Głogów铜区患者患智齿中汞含量的体外初步研究。

IF 6.8 Q1 TOXICOLOGY Journal of Xenobiotics Pub Date : 2023-08-27 DOI:10.3390/jox13030029
Sadri Rayad, Maciej Dobrzyński, Amadeusz Kuźniarski, Marzena Styczyńska, Dorota Diakowska, Tomasz Gedrange, Sylwia Klimas, Tomasz Gębarowski, Marzena Dominiak
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摘要

本研究的目的是测定Legnica-Głogów铜区居民受影响第三磨牙中的汞含量,以强调环境污染对人体的影响。72名患者参加了这项研究,他们的平均年龄为27.3±6.9岁。在这项研究中,研究组(Legnica-Głogów铜区居民)由51人组成,而对照组(弗罗茨瓦夫居民)由21名参与者组成。参与这项研究的女性人数更多(55人)。通过使用SpectraAA原子吸收光谱仪和使用空气-乙炔火焰的V2 AA240FS火焰附件的原子吸收光谱法测定样品中存在的汞的量。研究了居住在弗罗茨瓦夫的对照组成员牙齿中汞的积累,重点是确定导致这一现象的风险因素。最后的模型分析了各种因素的存在,包括甲状腺和甲状旁腺疾病、心脏疾病和间隔量表Vit。D3浓度。在这些因素中,心脏病的存在被认为与第三磨牙汞浓度的增加有关,具有统计学意义(比率=2.27,p<0.0001)。汞浓度随着年龄和居住在L-G铜区的时间而增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Mercury Content in Impacted Wisdom Teeth from Patients of the Legnica-Głogów Copper Area-An In Vitro Pilot Study.

The aim of this study was to determine the content of mercury in impacted third molars from Legnica-Głogów Copper Area residents to emphasize the effects of environmental pollution on the human body. A group of 72 patients with an average age of 27.3 ± 6.9 years participated in the study. Within this study, the research group (Legnica-Głogów Copper Area residents) comprised 51 individuals, while the control group (residents of Wrocław) consisted of 21 participants. A higher number of female individuals participated in the research (55). The amount of mercury present in the samples was determined through atomic absorption spectrometry with the use of a SpectraAA atomic absorption spectrometer and a V2 AA240FS flame attachment that utilized an air-acetylene flame. The accumulation of Hg in the teeth of members of the control group residing in Wrocław was studied, with a focus on identifying the risk factors that contribute to this phenomenon. The final model analyzed the presence of various factors, including thyroid and parathyroid gland diseases, cardiac diseases, and interval-scale Vit. D3 concentration. Among these factors, the presence of cardiac diseases was deemed statistically significant in relation to an increase in Hg concentration in third molars (rate ratio = 2.27, p < 0.0001). The concentration of mercury increased with the age and time of residence in the L-G Copper District.

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来源期刊
CiteScore
5.30
自引率
1.70%
发文量
21
审稿时长
10 weeks
期刊介绍: The Journal of Xenobiotics publishes original studies concerning the beneficial (pharmacology) and detrimental effects (toxicology) of xenobiotics in all organisms. A xenobiotic (“stranger to life”) is defined as a chemical that is not usually found at significant concentrations or expected to reside for long periods in organisms. In addition to man-made chemicals, natural products could also be of interest if they have potent biological properties, special medicinal properties or that a given organism is at risk of exposure in the environment. Topics dealing with abiotic- and biotic-based transformations in various media (xenobiochemistry) and environmental toxicology are also of interest. Areas of interests include the identification of key physical and chemical properties of molecules that predict biological effects and persistence in the environment; the molecular mode of action of xenobiotics; biochemical and physiological interactions leading to change in organism health; pathophysiological interactions of natural and synthetic chemicals; development of biochemical indicators including new “-omics” approaches to identify biomarkers of exposure or effects for xenobiotics.
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