闭锁综合征中的意识神经科学:预后和诊断回顾

Ibrain Pub Date : 2022-11-07 DOI:10.1002/ibra.12077
Berenika Maciejewicz
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引用次数: 0

摘要

这种被称为闭锁综合征的神经系统疾病是由脑干损伤引起的,通常是中风的后果。它的特点是完全瘫痪,意识和认知能力完好无损。人们对闭锁综合症患者的主观体验知之甚少。目前,还没有一个系统的评价方法来描述它们。最令人信服的资源来自于个人自己的话;然而,这些说法中只有一小部分得到了探索。当涉及到生物伦理学时,闭锁综合征协议几乎完全不存在。调查有这种情况的人对他们的连续性的感觉是很重要的。利用闭锁综合症对具身认知和意识水平提出问题,可以作为一个透镜,通过它来检查神经麻痹和交流的现象学问题。通过努力更好地理解这种情况,以及诸如“是什么使一个人成为一个人”这样的本体论问题,病人的护理和生活质量可能会得到改善。,“是什么让一个人出现在连续性中?”以及“什么是体现和主体间性的动力?”的问题可能会得到更好的探讨。本文旨在探讨闭锁综合征的一些生物医学因素,并为这种罕见的疾病提供一些预后和诊断建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Neuroscience of consciousness in the locked-in syndrome: Prognostic and diagnostic review

The neurological illness known as a locked-in syndrome is brought on by damage to the brainstem, usually as a consequence of a stroke. It is characterized by total paralysis with intact consciousness and cognitive capacity. The subjective experiences of people with locked-in syndrome are poorly understood. Presently, there is no systematic evaluation developed to describe them. The most compelling resources come from individuals’ own words; however, only a small fraction of these accounts have been explored. When it comes to bioethics, locked-in syndrome protocols are almost completely absent. Investigations on how people with this condition feel about their sense of continuity are of importance. Utilizing the locked-in syndrome to pose questions on embodied cognition and levels of consciousness could serve as a lens through which to examine problems in the phenomenology of neuroparalysis and communication. Care and quality of patients’ lives might be improved by an effort to understand this condition better, and ontological questions like “what makes a person a person?,” “what makes a person appear in continuity?,” and “what are the dynamics of embodiment and intersubjectivity?” might be better explored through that lens. This article aims to explore some biomedical factors that contribute to locked-in syndrome and offers some prognostic and diagnostic recommendations for this rare condition.

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