侵袭性念珠菌肺炎,与念珠菌性食管炎和胃炎相关,发生在一名可能具有免疫功能的患者身上。

Q4 Medicine Autopsy and Case Reports Pub Date : 2023-08-07 eCollection Date: 2023-01-01 DOI:10.4322/acr.2023.443
Devon Jackson, Lamarque Coke, Kamilah Fernandez, Kathriel Brister
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引用次数: 0

摘要

念珠菌肺炎仍然是一种难以诊断的疾病,最常见于免疫功能低下的个体。它很少在具有免疫活性的个体中报道。我们报告了一例在尸检中发现的与念珠菌性食管炎和胃炎相关的未经怀疑的念珠菌性肺炎,该患者可能具有免疫活性。患者为71岁男性,胸痛,随后发现心肌梗死,接受血管成形术和药物洗脱支架置入治疗。患者的康复因抗生素难治性肺炎而变得复杂,他经历了急性缺氧性呼吸衰竭、败血症、弥漫性血管内凝血(DIC),最终死亡。尸检显示有心肌梗死、白色念珠菌肺炎、食道炎和胃炎的证据。我们的病例强调了一个可能具有免疫活性的个体是如何发展这种感染的,以及念珠菌性食管炎和念珠菌性胃炎是如何与念珠菌性肺炎相关的。由于尸检难以诊断念珠菌肺炎,尸检为更好地了解这些病例以及可能导致其发展的因素提供了一个关键机会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Invasive Candida pneumonia, in association with Candida esophagitis and gastritis, in a presumably immunocompetent patient.

Candida pneumonia remains a difficult diagnosis and is most common in immunocompromised individuals. It has been rarely reported in immunocompetent individuals. We present a case of unsuspected Candida pneumonia associated with Candida esophagitis and gastritis discovered on postmortem examination in a presumably immunocompetent patient. The patient was a 71-year-old male who presented with chest pain and was subsequently found to have a myocardial infarction treated with angioplasty and drug-eluting stent placement. The patient's recovery was complicated by pneumonia refractory to antibiotics, and he went on to experience acute hypoxic respiratory failure, sepsis, disseminated intravascular coagulation (DIC), and ultimately expired. Autopsy revealed evidence of myocardial infarction as well as unsuspected Candida albicans pneumonia, esophagitis, and gastritis. Our case highlights how a presumably immunocompetent individual can develop this infection and how Candida esophagitis and Candida gastritis can be seen in association with Candida pneumonia. Due to the difficulty in diagnosing Candida pneumonia antemortem, autopsies provide a key opportunity to better understand these cases and the factors that may contribute to their development.

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Autopsy and Case Reports
Autopsy and Case Reports Medicine-Internal Medicine
CiteScore
1.20
自引率
0.00%
发文量
60
审稿时长
9 weeks
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