滇南小耳猪不同年龄组脑结构分析

Ibrain Pub Date : 2022-08-13 DOI:10.1002/ibra.12058
Yi-Fan Liu, Chang-Le Fang, Yu Pi, Teng-Fei Ke, Ji-Xiang Chu, Lin-Na Tang, Lan-Chun Zhang, Somjit Wanchana, Cheng-De Liao
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引用次数: 0

摘要

本研究采用磁共振成像(MRI)技术研究滇南小耳猪不同年龄脑发育及脑萎缩情况。选取滇南小耳猪12头,按年龄分为青壮年组、成年组和中老年组(M&O)。采用核磁共振成像技术对猪的大脑结构进行扫描,并对得到的大脑数据进行信号转换和图像重建等统计分析。与幼龄组比较,成年组和M&O组大部分脑结构信号明显减少(p < 0.05)。与成年组比较,M&O组右侧尾状核和右侧侧脑室信号强度显著升高,其他区域信号强度几乎显著降低(p < 0.05)。与青壮年组相比,成年组和M&O组均有不同程度的脑萎缩。与成年组相比,M&O组以楔前叶和颞下回脑萎缩为主。本研究表明,滇南小耳猪脑信号随年龄增长逐渐减弱,脑萎缩程度相反,为滇南小耳猪脑提供了基础数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Brain structure analysis of different age groups of Diannan small-ear pigs

The objective of the study is to investigate the brain development and atrophy of Diannan small-ear pigs in different ages using magnetic resonance imaging (MRI). A total of 12 Diannan small-ear pigs were included and divided into the young group, adult group, and middle-and-old age (M&O) group according to their age. The brain structure of pigs was scanned using MRI, and the brain data obtained were statistically analyzed by signal conversion and image reconstruction. Compared with the young group, the signals of most brain structures in the adult group and M&O group were significantly decreased (p < 0.05). Compared with the adult group, the signal intensity of the right caudate nucleus and the right lateral ventricle in the M&O group was significantly increased, while the signal intensity of other regions was almost significantly decreased (p < 0.05). Compared with the young group, both adult and M&O groups had some degree of brain atrophy. Brain atrophy in the precuneus and the inferior temporal gyrus was more predominant in the M&O group in comparison with the adult group. The present study demonstrated that the brain signal of Diannan small-ear pigs gradually diminished with age, while the degree of brain atrophy was the opposite, providing the basic data on the brain of Diannan small-ear pigs.

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