血小板在缺血条件下的作用。

Conditioning medicine Pub Date : 2018-10-01
Juan Alpuche, Luz Quírino, José T Sánchez-Vega, Jonathan Yap, Eduardo Pérez-Campos, Hector A Cabrera-Fuentes
{"title":"血小板在缺血条件下的作用。","authors":"Juan Alpuche,&nbsp;Luz Quírino,&nbsp;José T Sánchez-Vega,&nbsp;Jonathan Yap,&nbsp;Eduardo Pérez-Campos,&nbsp;Hector A Cabrera-Fuentes","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Ischemic heart disease (IHD) is one of the leading causes of death and disability worldwide. Platelets, as the main regulators of hemostasis, are major players in acute myocardial ischemia/reperfusion injury (IRI). Additionally, platelets are modified by endogenous cardioprotective strategies such as ischemic preconditioning, postconditioning, and remote ischemic conditioning. In this article, we provide an overview of the functionional role of platelets in acute myocardial IRI, and highlight their potential as targets for cardioprotection to improve health outcomes in patients with IHD.</p>","PeriodicalId":72686,"journal":{"name":"Conditioning medicine","volume":"1 6","pages":"313-318"},"PeriodicalIF":0.0000,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291202/pdf/nihms-997806.pdf","citationCount":"0","resultStr":"{\"title\":\"The Role of Platelets in Ischemic Conditioning.\",\"authors\":\"Juan Alpuche,&nbsp;Luz Quírino,&nbsp;José T Sánchez-Vega,&nbsp;Jonathan Yap,&nbsp;Eduardo Pérez-Campos,&nbsp;Hector A Cabrera-Fuentes\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Ischemic heart disease (IHD) is one of the leading causes of death and disability worldwide. Platelets, as the main regulators of hemostasis, are major players in acute myocardial ischemia/reperfusion injury (IRI). Additionally, platelets are modified by endogenous cardioprotective strategies such as ischemic preconditioning, postconditioning, and remote ischemic conditioning. In this article, we provide an overview of the functionional role of platelets in acute myocardial IRI, and highlight their potential as targets for cardioprotection to improve health outcomes in patients with IHD.</p>\",\"PeriodicalId\":72686,\"journal\":{\"name\":\"Conditioning medicine\",\"volume\":\"1 6\",\"pages\":\"313-318\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291202/pdf/nihms-997806.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Conditioning medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Conditioning medicine","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

缺血性心脏病(IHD)是世界范围内死亡和致残的主要原因之一。血小板作为止血的主要调节因子,是急性心肌缺血/再灌注损伤(IRI)的主要参与者。此外,血小板通过内源性心脏保护策略进行修饰,如缺血预处理、后处理和远程缺血预处理。在这篇文章中,我们概述了血小板在急性心肌IRI中的功能作用,并强调了它们作为心脏保护靶点的潜力,以改善IHD患者的健康状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

摘要图片

摘要图片

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The Role of Platelets in Ischemic Conditioning.

Ischemic heart disease (IHD) is one of the leading causes of death and disability worldwide. Platelets, as the main regulators of hemostasis, are major players in acute myocardial ischemia/reperfusion injury (IRI). Additionally, platelets are modified by endogenous cardioprotective strategies such as ischemic preconditioning, postconditioning, and remote ischemic conditioning. In this article, we provide an overview of the functionional role of platelets in acute myocardial IRI, and highlight their potential as targets for cardioprotection to improve health outcomes in patients with IHD.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Targeting leukotriene biosynthesis to prevent atherosclerotic cardiovascular disease. Commentary: Can astrocytic mitochondria therapy be used as antioxidant conditioning to protect neurons? Preclinical evaluation of circadian rhythm in ischemic stroke outcomes. Conditioning medicine for ischemic and hemorrhagic stroke. Mitochondria as the memory of preconditioning.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1