Shaobao Liu, Ru Tao, Ming Wang, Jin Tian, Guy M Genin, Tian Jian Lu, Feng Xu
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Regulation of Cell Behavior by Hydrostatic Pressure.
Hydrostatic pressure (HP) regulates diverse cell behaviors including differentiation, migration, apoptosis, and proliferation. Abnormal HP is associated with pathologies including glaucoma and hypertensive fibrotic remodeling. In this review, recent advances in quantifying and predicting how cells respond to HP across several tissue systems are presented, including tissues of the brain, eye, vasculature and bladder, as well as articular cartilage. Finally, some promising directions on the study of cell behaviors regulated by HP are proposed.
期刊介绍:
Applied Mechanics Reviews (AMR) is an international review journal that serves as a premier venue for dissemination of material across all subdisciplines of applied mechanics and engineering science, including fluid and solid mechanics, heat transfer, dynamics and vibration, and applications.AMR provides an archival repository for state-of-the-art and retrospective survey articles and reviews of research areas and curricular developments. The journal invites commentary on research and education policy in different countries. The journal also invites original tutorial and educational material in applied mechanics targeting non-specialist audiences, including undergraduate and K-12 students.