严重急性呼吸系统综合征冠状病毒2型后的垂直传播和母体被动免疫。

IF 2.1 4区 医学 Q3 VIROLOGY Future Virology Pub Date : 2023-08-01 Epub Date: 2023-10-04 DOI:10.2217/fvl-2023-0089
Hanie Karimi, Vahid Mansouri, Nima Rezaei
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引用次数: 0

摘要

自2020年以来,严重急性呼吸系统综合征冠状病毒2型的高度传染性和各种传播途径使疫情无休止。通过胎盘和母乳的垂直传播(VT)在某些病毒类型中很常见,被认为存在严重急性呼吸系统综合征冠状病毒2型,许多研究人员对此进行了假设。相反,产生抗体是为了抵消病毒的影响。由于新生儿的免疫系统不能产生适当的抗体,母体抗体通常会从母亲转移到婴儿/胎儿身上以满足需求。这一理论导致了严重急性呼吸系统综合征冠状病毒2型感染或接种疫苗后抗体通过胎盘和母乳传播的假设。本文进一步讨论了这些假设,考虑到胎儿/婴儿伤害与利益的后果。
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Vertical transmission and maternal passive immunity post-SARS-CoV-2.

Since 2020, the highly contagious nature and various transmission routes of SARS-CoV-2 have rendered the pandemic interminable. Vertical transmission (VT) through the placenta and breast milk, which is frequent for certain virus types, is thought to exist for SARS-CoV-2 and is hypothesized by many researchers. Conversely, antibodies are produced to counteract the effect of viruses. Since newborns' immunologic system cannot produce proper antibodies, maternal antibodies are usually transferred from mother to infant/fetus to meet the need. This theory leads to the hypothesis of transmission of antibodies through the placenta and breast milk following SARS-CoV-2 infection or vaccination. This paper further discusses these hypotheses, considering consequences of fetus/infant harm versus benefit.

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来源期刊
Future Virology
Future Virology 医学-病毒学
CiteScore
4.00
自引率
3.20%
发文量
84
审稿时长
6-12 weeks
期刊介绍: Future Virology is a peer-reviewed journal that delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this ever-expanding area of research. It is an interdisciplinary forum for all scientists working in the field today.
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