{"title":"大麻的使用：神经生物学、行为学和性别/性别因素。","authors":"Anahita Bassir Nia, Claire Mann, Harsimar Kaur, Mohini Ranganathan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>To summarize the current literature on the effects of cannabinoids in humans and to discuss the existing literature on the sex- and gender-related differences in the effects of cannabinoids.</p><p><strong>Recent findings: </strong>Cannabis and its constituent cannabinoids are associated with risk of addiction, cognitive deficits and mood/psychotic disorders. Preclinical and emerging clinical data suggest greater sensitivity to the effects of cannabinoids in women.</p><p><strong>Summary: </strong>Cannabis is one of the most commonly used drugs with increasing rates of use. Women in particular may be at a greater risk of adverse outcomes given the previously described \"telescoping effect\" of substance use in women. Human data examining the sex- and gender-related differences in the effects of cannabinoids and factors underlying these differences are very limited. This represents a critical gap in the literature and needs to be systematically examined in future studies.</p>","PeriodicalId":36384,"journal":{"name":"Current Behavioral Neuroscience Reports","volume":"5 4","pages":"271-280"},"PeriodicalIF":2.1000,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756752/pdf/nihms-1512214.pdf","citationCount":"0","resultStr":"{\"title\":\"Cannabis Use: Neurobiological, Behavioral, and Sex/Gender Considerations.\",\"authors\":\"Anahita Bassir Nia, Claire Mann, Harsimar Kaur, Mohini Ranganathan\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose of review: </strong>To summarize the current literature on the effects of cannabinoids in humans and to discuss the existing literature on the sex- and gender-related differences in the effects of cannabinoids.</p><p><strong>Recent findings: </strong>Cannabis and its constituent cannabinoids are associated with risk of addiction, cognitive deficits and mood/psychotic disorders. Preclinical and emerging clinical data suggest greater sensitivity to the effects of cannabinoids in women.</p><p><strong>Summary: </strong>Cannabis is one of the most commonly used drugs with increasing rates of use. Women in particular may be at a greater risk of adverse outcomes given the previously described \\\"telescoping effect\\\" of substance use in women. Human data examining the sex- and gender-related differences in the effects of cannabinoids and factors underlying these differences are very limited. This represents a critical gap in the literature and needs to be systematically examined in future studies.</p>\",\"PeriodicalId\":36384,\"journal\":{\"name\":\"Current Behavioral Neuroscience Reports\",\"volume\":\"5 4\",\"pages\":\"271-280\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2018-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756752/pdf/nihms-1512214.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Behavioral Neuroscience Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2018/11/10 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Behavioral Neuroscience Reports","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2018/11/10 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Cannabis Use: Neurobiological, Behavioral, and Sex/Gender Considerations.
Purpose of review: To summarize the current literature on the effects of cannabinoids in humans and to discuss the existing literature on the sex- and gender-related differences in the effects of cannabinoids.
Recent findings: Cannabis and its constituent cannabinoids are associated with risk of addiction, cognitive deficits and mood/psychotic disorders. Preclinical and emerging clinical data suggest greater sensitivity to the effects of cannabinoids in women.
Summary: Cannabis is one of the most commonly used drugs with increasing rates of use. Women in particular may be at a greater risk of adverse outcomes given the previously described "telescoping effect" of substance use in women. Human data examining the sex- and gender-related differences in the effects of cannabinoids and factors underlying these differences are very limited. This represents a critical gap in the literature and needs to be systematically examined in future studies.
期刊介绍：
Under the leadership of Emil Coccaro, Current Behavioral Neuroscience Reports will provide an in-depth review of topics covering personality and impulse control disorders, psychosis, mood and anxiety disorders, genetics and neuroscience, geropsychiatry and cognitive disorders of late life, child and developmental psychiatry, addictions, and neuromodulation.We accomplish this aim by inviting international authorities to contribute review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. By providing clear, insightful balanced contributions, the journal intends to serve those involved in the field of behavioral neuroscience.
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