Sugammadex诱发支气管痉挛1例。

Saeyoung Kim, Hyojun Choo, Hoon Jung, Ji Hyun Kim
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引用次数: 0

摘要

Sugammadex对甾体类神经肌肉阻滞(NMB)的拮抗速度快于传统的NMB拮抗剂新斯的明,即使在强拮抗阶段也是如此。这种效率是可能的,因为通过封装NMB分子的独特作用机制。因此,使用sugammadex也可以避免与胆碱能系统的直接相互作用及其随后的副作用,这是传统药物的缺点。然而,尽管有这些益处,并且美国食品药品监督管理局(FDA)在2015年批准了这些益处,但仍有与sugammadex相关的罕见不良事件报告。在此,我们报告一例sugammadex给药后立即发生的支气管痉挛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Sugammadex-induced bronchospasm: a case report.

Sugammadex has shown faster reversal of steroidal neuromuscular blockade (NMB) than neostigmine, a traditional reversal agent for NMB, even in the intense block phase. This efficiency is possible because of the unique mechanism of action by encapsulating the NMB molecules. Therefore, with the use of sugammadex, we can also expect to avoid direct interactions with the cholinergic system and its subsequent side effects, which are disadvantages of traditional drugs. However, despite these benefits and US Food and Drug Administration (FDA) approval in 2015, rare adverse events associated with sugammadex have been reported. Herein, we report a case of bronchospasm that developed immediately after sugammadex administration.

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