Chinese guidelines for diagnosis and treatment of gastric cancer 2018 (English version)

1. Overview 2. Diagnosis 2.1 Symptoms 2.2 Signs 2.3 Imaging 2.3.1 X-ray gas-barium double-contrast imaging 2.3.2 Ultrasonography (US) 2.3.3 CT 2.3.4 MRI 2.3.5 Positron emission tomography (PET)-CT 2.3.6 Emission computerized tomography (ECT) 2.3.7 Tumor biomarkers 2.3.8 Endoscopy 2.3.9 EUS 2.4 Diagnostic criteria and contents of gastric cancer 2.4.1 Qualitative diagnosis 2.4.2 Staging diagnosis 2.4.3 Clinical manifestations 2.5 Differential diagnosis 2.5.1 Benign gastric ulcer 2.5.2 Gastric lymphoma 2.5.3 Gastrointestinal stromal tumor 2.5.4 Neuroendocrine neoplasm (NEN) 2.5.5 Benign gastric tumor 3. Pathology specification 3.1 Terms and definitions 3.1.1 Gastric carcinoma 3.1.2 Intraepithelial neoplasia/dysplasia 3.1.3 Early gastric carcinoma 3.1.4 Advanced gastric carcinoma 3.1.5 Adenocarcinoma of EGJ 3.2 Specimen type and fixation 3.2.1 Specimen type 3.2.2 Specimen fixation 3.3 Norm of handling and describing specimens 3.3.1 Handling of biopsy specimen 3.3.2 Handling of endoscopically resected specimens (EMR/ESD) 3.3.3 Handling of resected specimen 3.4 Classification, grade and staging of pathological diagnosis 3.4.1 Histological type (Appendix 3) 3.4.2 Histological grade 3.4.3 Gastric cancer staging 3.4.4 Pathological evaluation of radical resection specimens after neoadjuvant therapy (Appendix 4) 3.5