利用快速分子测试(RMT/RIF)在印度尼西亚发现结核病药物敏感/耐药:一项试点研究

IF 0.4 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Kesmas-National Public Health Journal Pub Date : 2023-09-04 DOI:10.21109/kesmas.v18isp1.6875
M. Herawati, Dasuki Dasuki, D. Lolong, Mirna Widiyanti, Betty Roosihermiatie, Ria Yuda Permata, Raflizar Raflizar, Ferry Ahmadi, Hadi Supratikta, M. Veruswati
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引用次数: 0

摘要

结核病(TB)指标的漏诊和漏报是尚未解决的问题。快速分子检测(RMT)通过使用更安全和更敏感的设备,是结核病病例发现方面的突破之一;它甚至被认为有助于发现耐药结核病。一个结核病项目定期举办的几次网络研讨会的结果,以及该项目的评估和RMT的使用,构成了本研究的基础。这项初步的试点研究旨在概述使用RMT治疗药物敏感和耐药结核病的病例发现情况。对印度尼西亚几个省份的样本进行了横断面研究,这些省份在偏远或非偏远岛屿边界地区和财政能力方面都采用了RMT。在使用RMT发现药物敏感结核病病例方面,最大的贡献者是15岁以上的男性,而在耐药结核病病例发现组中,最大的贡献者是2017年和2018年使用RMT。总的来说,研究结果只能描述研究区域的情况。如果检测到的病例是年龄在15岁以上的男性,那么RMT在药物敏感结核病例发现中的使用将得到最大化,而RMT可以帮助发现耐药结核病例。
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Utilizing Rapid Molecular Tests (RMT/RIF) in Tuberculosis Drug-Sensitive/Resistant Discovery in Indonesia: A Pilot Study
The underdiagnosis and underreporting of tuberculosis (TB) indicators are unresolved problems. The rapid molecular test (RMT) is one of the breakthroughs for TB case finding by using safer and more sensitive equipment; it is even believed to help find drug-resistant TB. The results of several webinars held regularly by a TB program as well as its evaluation and the use of RMT formed the basis of this study. This initial pilot study aimed to provide an overview of case finding for both drug-sensitive and drug-resistant TB using RMT. A cross-sectional study was conducted on samples in several provinces in Indonesia that have used RMT, both in remote or non-remote island borders areas and fiscal capacity. Regarding the use of RMT for drug-sensitive TB case finding, the largest contributors were males aged above 15 years, while in the drug-resistant TB case finding group, the biggest contributor was the use of RMT in 2017 and 2018. Overall, the findings could only describe the situation in the study area. The use of RMT in drug-sensitive TB case finding would be maximized if the detected cases are males aged above 15 years, while RMT can help find cases of drug-resistant TB.
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来源期刊
Kesmas-National Public Health Journal
Kesmas-National Public Health Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.70
自引率
0.00%
发文量
39
审稿时长
10 weeks
期刊最新文献
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