左、右结肠癌患者特征的差异——单中心体验

Q4 Medicine Libri Oncologici Pub Date : 2020-01-29 DOI:10.20471/lo.2019.47.02-03.08
Darko Kotromanović, Z. Kotromanović, Ilijan Tomaš, Josipa Flam, Sonja Kotromanović, Ž. Kotromanović, Mirela Penc-Šambić
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引用次数: 0

摘要

目的:本研究的目的是确定2010年1月1日至2012年12月31日期间在奥西耶克临床医学中心肿瘤诊所接受治疗的结直肠癌患者,根据肿瘤在左结肠或右结肠的位置,到复发或转移灶出现的时间差异。研究设计:历史前瞻性研究材料和方法:研究纳入的患者数据来自奥西耶克临床医学中心肿瘤诊所的医疗档案。关于病人死亡的数据由克罗地亚共和国登记办公室记录。结果:纳入272例患者,其中男性160例(58.8%),女性112例(41.2%)。按部位分,左侧结肠肿瘤211例(77.6%),右侧结肠肿瘤61例(22.4%)。中位年龄为67岁。右侧结肠肿瘤较大,中位直径为6cm,中位数为16个。出现转移的中位时间为20个月(四分位数范围为8至29个月);右侧结肠肿瘤时间明显缩短。205例(75.4%)患者获得了治疗的积极结果,与结肠癌定位相比无显著差异。通过对患者生存率的Kaplan-Meier分析,右侧结肠肿瘤患者的总5年生存率为72%,而左侧结肠肿瘤患者的5年生存率为62%。结论:本研究证实结直肠癌的发病部位存在差异。右侧结肠癌患者年龄较大,癌体较大,右侧结肠癌出现复发或转移的时间较短,左侧结肠癌5年生存率较低。
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The difference between left and right colon cancer patients’ characteristics - single center experience
Summary Objectives : The purpose of the study was to determine the difference in time until the appearance of relapse or metas tases in patients treated for colorectal cancer, depending on the location of the tumor in the left or right colon at the oncology clinic of clinical Medical centre osijek between 1 st January 2010 and 31 st December 2012. Study design : historical prospective study Material and methods : study included patients whose data were recorded from medical archive at the oncology clinic of Clinical Medical Centre Osijek. The data on patients’ deaths were recorded from the Registry Office of the Republic of croatia. Results : the study included 272 patients, 160 (58.8%) men and 112 (41.2%) women. according to the location, left sided colon tumor was discovered in 211 (77.6%) patients and right-sided in 61 (22.4%). the median age was 67 years. right-sided colon tumors are considerably larger with median diameter of 6 cm, with median number of 16. Median of time until the appearance of the metastases is 20 months (interquartile range is from 8 to 29 months); marked time being shorter in right-sided colon tumors. Positive outcome of the treatment was achieved in 205 (75.4%) patients, with no significant difference in com parison to the colon cancer localization. By using Kaplan-Meier analysis of patients’ survival rates, a total 5- year survival rate of 72% was achieved in right-sided colon tumor in comparison to 62% in patients with the left-sided colon tumor. Conclusion : This study confirms that there is a difference in colorectal cancer according to its localisation. Patients with right-sided colorectal cancer are older, the carcinoma is larger, the time until the appearance of a relapse or a metastases is shorter in right sided colon cancer while 5-year survival rate is lower in left sided colon cancer.
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来源期刊
Libri Oncologici
Libri Oncologici Medicine-Oncology
CiteScore
0.30
自引率
0.00%
发文量
9
审稿时长
8 weeks
期刊介绍: - Genitourinary cancer: the potential role of imaging - Hemoglobin level and neoadjuvant chemoradiation in patients with locally advanced cervical carcinoma
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