脂质体及其对皮肤癌破坏的单调作用

IF 4.1 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Frontiers in Nanotechnology Pub Date : 2023-01-12 DOI:10.3389/fnano.2023.1087413
Prafull Shinde, A. Page, Sankha Bhattacharya
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引用次数: 1

摘要

癌症是影响世界各大洲的最突出的疾病之一,死亡率和发病率显著上升。常规治疗,包括化疗和手术,有一些缺点。染色体系统将在本汇编中进行全面审查,并根据组成对其进行分类:经典染色体、二元染色体和跨染色体。染色体系统是含有大量乙醇的模型脂质囊泡载体。本章全面回顾了醇体系统成分、制备技术的影响,以及它们在选择这些纳米载体的最终特性中的主要作用。本章介绍了醇质体的特殊技术,包括冷法、热法、注射法、机械分散法和常规方法。还解释了染色体的各种评价参数。此外,醇溶体凝胶、贴剂和乳膏可以作为创新的药物配方来强调。一些具有纳米药物联合治疗癌症的混合染色体囊泡可以克服特定癌症细胞目前的耐药性。通过使用再利用疗法,可以更有效地输送植物成分。广泛的体内模型被用来评估它们的有效性。染色体体在未来提供了许多潜在的皮肤癌症治疗方法。
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Ethosomes and their monotonous effects on Skin cancer disruption
Skin cancer is one of the most prominent diseases, affecting all continents worldwide, and has shown a significant rise in mortality and prevalence. Conventional therapy, including chemotherapy and surgery, has a few drawbacks. The ethosomal systems would be thoroughly reviewed in this compilation, and they would be classified based on constituents: classical ethosomes, binary ethosomes, and transethosomes. Ethosomes systems are model lipid vesicular carriers with a substantial portion of ethanol. The impacts of ethosomal system components, preparation techniques, and their major roles in selecting the final characteristics of these nanocarriers are comprehensively reviewed in this chapter. The special techniques for ethosomes, including the cold approach, hot approach, injection method, mechanical dispersion method, and conventional method, are explained in this chapter. Various evaluation parameters of ethosomes were also explained. Furthermore, ethosomal gels, patches, and creams can be emphasised as innovative pharmaceutical drug formulations. Some hybrid ethosomal vesicles possessing combinatorial cancer therapy using nanomedicine could overcome the current drug resistance of specific cancer cells. Through the use of repurpose therapy, phytoconstituents may be delivered more effectively. A wide range of in vivo models are employed to assess their effectiveness. Ethosomes have provided numerous potential skin cancer therapeutic approaches in the future.
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来源期刊
Frontiers in Nanotechnology
Frontiers in Nanotechnology Engineering-Electrical and Electronic Engineering
CiteScore
7.10
自引率
0.00%
发文量
96
审稿时长
13 weeks
期刊最新文献
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