Chemical Applicability of Second Order Sombor Index

In this paper, we introduce the higher-order Sombor index of a molecular graph. In addtition, we compute the second order Sombor index of some standard class of graphs and line graph of subdivision graph of 2D-lattice, nanotube and nanotorus of TUC_4C_8[p,q] and also we obtain the expressions of the second order Sombor index of the line graph of subdivision graph of tadpole graph, wheel graph, ladder graph and chain silicate network CSn. Further, we study the linear regression analysis of the second order Sombor index with the entropy, acentric factor, enthalpy of vaporization and standard enthalpy of vaporization of an octane isomers.