尼日利亚索科托专科医院高血压患者的一些全血细胞计数参数

O. Erhabor, Abdullah Shehu, T. Erhabor, T. C. Adias, Iwueke Ip
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引用次数: 5

摘要

高血压(HTN)是世界范围内的一个主要健康问题。它可能导致心血管疾病和功能紊乱,包括血液学参数。2018年6月至9月,研究了60名连续招募的高血压受试者和30名年龄匹配的非高血压对照者的全血细胞计数(FBC)参数。对受试者和对照参与者的乙二胺四乙酸(EDTA)抗凝血液和血清进行FBC分析。与非高血压对照组相比,高血压受试者的总白细胞计数(WBC)、堆积细胞体积(PCV)血红蛋白(Hb)、中性粒细胞和嗜酸性粒细胞显著降低(p分别为40岁和<40岁(p分别=0.02和0.01)。女性高血压患者的红细胞计数显著高于男性(p=0.05)。男性高血压患者的血红蛋白和单核细胞计数分别显著高于女性高血压患者(p=0.02和0.04)。豪萨族高血压受试者的单核细胞计数显著高于富拉尼族(t=2.79,p<0.01)。本研究结果表明,与非高血压对照组相比,高血压受试人群的WBC、PCV、Hb、中性粒细胞和嗜酸性粒细胞显著降低。疾病分期、年龄、性别和种族对高血压患者的FBC参数有显著影响。有必要加强公众启蒙计划,教育高血压患者定期去诊所进行有效随访的必要性。建议提供该地区高血压患者FBC参数的常规监测设施。
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Some Full Blood Count Parameters among Hypertensive Patients Attending Specialist Hospital, Sokoto, Nigeria
Hypertension (HTN) is a major health problem worldwide. It can lead to cardiovascular disease and functional disturbances including haematological parameters. Full blood count (FBC) parameters of a total of 60 consecutively-recruited hypertensive subjects and 30 age-matched non-hypertensive controls were studied between June and September, 2018. Ethylene Diamine Tetra Acetic Acid (EDTA) anticoagulated blood and serum from subjects and control participants were analyzed for FBC. The total white cell count (WBC), packed cell volume (PCV) haemoglobin (Hb), neutrophils and eosinophils were significantly lower among hypertensive subjects compared to non-hypertensive controls (p 40-year-old compared to those <40 years of age (p = 0.02 and 0.01) respectively. The RBC count was significantly higher among female compared to male hypertensives (p = 0.05). The haemoglobin and monocyte count were significantly higher among male compared to female hypertensives (p = 0.02 and 0.04) respectively. The monocyte count was significantly higher among hypertensive subjects of Hausa ethnic group compared to Fulani (t = 2.79, p < 0.01). The findings from this study indicates that the WBC, PCV, Hb, neutrophils and eosinophils were significantly lower among hypertensive subjects compared to non-hypertensive controls. Stage of the disease, age, gender and ethnicity had a significant effect on the FBC parameters of the hypertensive patients. There is need to step up public enlightenment programme to educate hypertensive patients on the need for attending clinic regularly for effective follow up. It is recommended that facilities for the routine monitoring of FBC parameters among hypertensive in the area be provided.
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