抗精神病药恶性综合征诱发肌红蛋白铸型肾病1例

Pub Date : 2024-09-01 Epub Date: 2023-06-05 DOI:10.4103/ijn.ijn_137_23

Prem S Patel, Prit P Singh, Archana, Om Kumar

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引用次数: 0

摘要

肌红蛋白铸型肾病是横纹肌溶解症的后遗症，其特征是游离肌红蛋白在血液循环中释放、近端曲小管直接损伤以及远端曲小管被肌红蛋白铸型阻塞。我们报告了一例有趣的肌红蛋白铸型肾病病例，患者曾服用神经安定药物，并出现神经安定恶性综合征和急性肾损伤。

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A Case of Neuroleptic Malignant Syndrome-Prompted Myoglobin Cast Nephropathy.

Myoglobin cast nephropathy is a sequel of rhabdomyolysis, and is characterized by the release of free myoglobin in the circulation, direct proximal convoluted tubule injury, and obstruction by myoglobin cast in distal tubules. We report an interesting case of myoglobin cast nephropathy in a patient who was on neuroleptic drugs and who presented with neuroleptic malignant syndrome and acute kidney injury.

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