{"title":"叠氮-乌吉四元反应合成α-磺酰氨基四唑","authors":"C. I. Jesin, R. Kataria, G. Nandi","doi":"10.1055/a-1981-9151","DOIUrl":null,"url":null,"abstract":"The sulfoximine based tetrazoles have been synthesized via Azido-Ugi four component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 ℃ in the presence of InCl3. Replacement of sulfoximine with sulfonimidamide (SIA) have delivered corresponding SIA based tetrazole. Interestingly, SIA is also acting as a surrogate amine to accomplish corresponding aminotetrazole as by-product.","PeriodicalId":22135,"journal":{"name":"SynOpen","volume":null,"pages":null},"PeriodicalIF":2.0000,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction\",\"authors\":\"C. I. Jesin, R. Kataria, G. Nandi\",\"doi\":\"10.1055/a-1981-9151\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The sulfoximine based tetrazoles have been synthesized via Azido-Ugi four component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 ℃ in the presence of InCl3. Replacement of sulfoximine with sulfonimidamide (SIA) have delivered corresponding SIA based tetrazole. Interestingly, SIA is also acting as a surrogate amine to accomplish corresponding aminotetrazole as by-product.\",\"PeriodicalId\":22135,\"journal\":{\"name\":\"SynOpen\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2022-10-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SynOpen\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/a-1981-9151\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SynOpen","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-1981-9151","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Synthesis of α-Sulfoximino Tetrazoles via Azido-Ugi Four-Component Reaction
The sulfoximine based tetrazoles have been synthesized via Azido-Ugi four component reactions of sulfoximines, isocyanides, aldehydes, and TMS-azide in MeOH at 70 ℃ in the presence of InCl3. Replacement of sulfoximine with sulfonimidamide (SIA) have delivered corresponding SIA based tetrazole. Interestingly, SIA is also acting as a surrogate amine to accomplish corresponding aminotetrazole as by-product.
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