用于疼痛评估的贝叶斯网络概念(预印本)

O. Sadik
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引用次数: 0

摘要

非结构性疼痛是一种主观现象,主要由身体、生理或社会影响引起/感知。目前,最常用的疼痛测量方法依赖于在离散评分表上自我报告疼痛水平。这提供了疼痛的主观且仅有半定量的指标。本文提出了一种方法,将自我报告的疼痛与疼痛相关的生物标志物相结合,从生物传感器(正在开发中)和可能的其他证据来源中获得,以提供对体验疼痛的更可靠估计,这是一种临床决策支持系统。我们使用贝叶斯网络来说明该方法,但也描述了其他提供其他方法来组合证据的人工智能(AI)方法。我们还提出了一种优化人工智能方法参数的方法(对临床医生来说是不透明的),以便最好地近似对医生最有用的输出类型。我们从379名患者的样本中提供了一些数据,这些数据说明了我们在实际医疗情况下可能预期的几种证据模式。我们的大多数(79.7%)患者显示出一致的证据,表明这种生物标志物方法可能是合理的。我们还发现了五种不一致的证据模式。这些都为进一步探索指明了方向。最后,我们概述了一种收集医学专家指导的方法,以提供最有用的指导(任何优化方法都需要)。我们认识到,一个可能的结果可能是,所有这些方法可能能够提供的是对证据一致性或不一致性程度的量化衡量,将最终决定权留给临床医生(必须驻留在哪里)。在某些情况下,指向其他证据来源也是可能的。
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A Bayesian Network Concept for Pain Assessment (Preprint)
UNSTRUCTURED Pain is a subjective phenomenon caused/perceived centrally and modified by physical, physiological, or social influences. Currently, the most commonly used approaches for pain measurement rely on self-reporting of pain level on a discrete rating scale. This provides a subjective and only semi-quantitative indicator of pain. This paper presents an approach that combines self-reported pain with pain-related biomarkers to be obtained from biosensors (in development) and possibly other sources of evidence to provide more dependable estimates of experienced pain, a clinical decision support system. We illustrate the approach using a Bayes network, but also describe other artificial intelligence (AI) methods that provide other ways to combine evidence. We also propose an optimization approach for tuning the AI method parameters (opaque to clinicians) so as to best approximate the kinds of outputs most useful to medical practitioners. We present some data from a sample of 379 patients that illustrate several evidence patterns we may expect in real healthcare situations. The majority (79.7%) of our patients show consistent evidence suggesting this biomarker approach may be reasonable. We also found five patterns of inconsistent evidence. These suggest a direction for further exploration. Finally, we sketch out an approach for collecting medical experts’ guidance as to the way the combined evidence might be presented so as to provide the most useful guidance (also needed for any optimization approach). We recognize that one possible outcome may be that all this approach may be able to provide is a quantified measure of the extent to which the evidence is consistent or not, leaving the final decision to the clinicians (where it must reside). Pointers to additional sources of evidence might also be possible in some situations.
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