Toshichika Kanagawa, H. Maeda, K. Okamoto, Ian Fukudome, Sachi Tsuda, T. Namikawa, Michiya Kobayashi, K. Hanazaki
{"title":"一例接受抗白细胞介素-6受体单克隆抗体治疗的升结肠癌症穿孔急诊手术后腹膜后脓肿的非典型表现和延长","authors":"Toshichika Kanagawa, H. Maeda, K. Okamoto, Ian Fukudome, Sachi Tsuda, T. Namikawa, Michiya Kobayashi, K. Hanazaki","doi":"10.4993/acrt.27.42","DOIUrl":null,"url":null,"abstract":"Tocilizumab is an anti-interleukin-6 receptor monoclonal antibody which was recently approved for the treatment of inflammatory arthritis and Castleman disease. Because tocilizumab suppresses immunological reactions, the more frequent occurrence of infections with atypical presentations is a conceivable complication after abdominal surgery. Herein, we would like to describe a case of a prolonged abdominal abscess with subtle abdominal pain after surgery for perforated ascending colon cancer in a patient with Castleman disease treated by tocilizumab.","PeriodicalId":35647,"journal":{"name":"Annals of Cancer Research and Therapy","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Atypical presentation and prolongation of retroperitoneal abscess after emergency surgery for perforated ascending colon cancer in a patient receiving anti-interleukin-6 receptor monoclonal antibody therapy\",\"authors\":\"Toshichika Kanagawa, H. Maeda, K. Okamoto, Ian Fukudome, Sachi Tsuda, T. Namikawa, Michiya Kobayashi, K. Hanazaki\",\"doi\":\"10.4993/acrt.27.42\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tocilizumab is an anti-interleukin-6 receptor monoclonal antibody which was recently approved for the treatment of inflammatory arthritis and Castleman disease. Because tocilizumab suppresses immunological reactions, the more frequent occurrence of infections with atypical presentations is a conceivable complication after abdominal surgery. Herein, we would like to describe a case of a prolonged abdominal abscess with subtle abdominal pain after surgery for perforated ascending colon cancer in a patient with Castleman disease treated by tocilizumab.\",\"PeriodicalId\":35647,\"journal\":{\"name\":\"Annals of Cancer Research and Therapy\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Cancer Research and Therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4993/acrt.27.42\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Cancer Research and Therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4993/acrt.27.42","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Atypical presentation and prolongation of retroperitoneal abscess after emergency surgery for perforated ascending colon cancer in a patient receiving anti-interleukin-6 receptor monoclonal antibody therapy
Tocilizumab is an anti-interleukin-6 receptor monoclonal antibody which was recently approved for the treatment of inflammatory arthritis and Castleman disease. Because tocilizumab suppresses immunological reactions, the more frequent occurrence of infections with atypical presentations is a conceivable complication after abdominal surgery. Herein, we would like to describe a case of a prolonged abdominal abscess with subtle abdominal pain after surgery for perforated ascending colon cancer in a patient with Castleman disease treated by tocilizumab.
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