一例罕见的慢性空腔性肺曲霉菌病

S. Das, Soumyadeep Ghosh, Gopal Sasmal
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引用次数: 0

摘要

曲霉属引起广泛的肺部疾病,包括过敏性、腐生性、半侵袭性和侵袭性曲霉菌病。宿主免疫系统是人类疾病模式的主要决定因素。曲霉菌感染的几种慢性形式已被描述,包括慢性空洞性肺曲霉菌病(CCPA)、慢性纤维化肺曲霉血症(CFPA)和慢性坏死性肺曲霉病(CNPA)。慢性空洞性肺曲霉菌病通常是一个渐进的过程,影响明显具有免疫功能的先前存在肺部疾病的个体。诊断取决于是否存在体质和肺部症状、提示性放射学变化以及曲霉菌感染的微生物学或血清学证据。我们在此报告一例28岁的免疫功能正常男性,其既往有肺结核病史,随后被诊断为慢性空洞性肺曲霉菌病。
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A case of chronic cavitory pulmonary aspergillosis, a rare entity
Aspergillus species cause a wide spectrum of pulmonary disease including allergic, saprophytic, semi-invasive and invasive aspergillosis. Host immune system is the major determinant of the pattern of illness in human beings. Several chronic forms of Aspergillus infections have been described which include chronic cavitary pulmonary aspergillosis (CCPA), chronic fibrotic pulmonary aspergillosis (CFPA) and chronic necrotizing pulmonary aspergillosis (CNPA). Chronic cavitary pulmonary aspergillosis usually runs a progressive course, affects apparently immunocompetent individuals with a pre-existing lung disease. Diagnosis depends on presence of constitutional and pulmonary symptoms, suggestive radiological changes and microbiological or serological evidence of Aspergillus infection. We hereby present a case of 28 years immunocompetent male who had prior history of pulmonary tuberculosis and was subsequently diagnosed as chronic cavitary pulmonary aspergillosis.
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