不同方法预防肝硬化胃食管出血的疗效对比分析

F. Nazyrov, A. V. Devyatov, A. Babadjanov, U. Makhmudov, O. A. Omonov
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引用次数: 1

摘要

目标评价肝硬化患者预防胃食管出血的临床疗效。材料和方法。从2008年到2019年,考虑了710名肝硬化患者的手术治疗。对三组患者预防胃食管静脉曲张再出血的长期结果进行了研究:门体分流术(367名患者)、食管胃完全断开术(62名患者)和内镜手术(281名患者)。观察期从1个月到115个月不等。后果分流术后再出血率最低,为15.5%(χ2=9.728;df=2;р=0.008),而内镜治疗后的再出血率最高,为40.9%。到随访的第5年,只有37.5%的患者在内镜手术后没有出血迹象。在分流术、食管胃完全断开术和内镜手术后,未经历真正的胃食管静脉曲张再出血的患者比例分别为44%、76%和85%(p<0.05)。结论:无论选择何种手术,所有肝硬化患者都会长期发生门脉再出血。然而,门体分流术后再出血率最低。
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Efficacy of different methods for preventing gastroesophageal bleeding in patients with liver cirrhosis: comparative analysis
Aim. To assess the clinical efficacy of preventing gastroesophageal bleeding in patients with liver cirrhosis.Materials and methods. From 2008 to 2019, the surgical treatment of 710 patients with cirrhosis was considered. The long-term results of preventing gastroesophageal variceal rebleeding were studied in three groups of patients: portosystemic shunt placement (367 patients), total esophagogastric disconnection (62 patients), and endoscopic procedures (281 patients). Observation periods varied from 1 to 115 months.Results. The lowest rebleeding rate of 15.5% was observed following shunt placement (χ2 = 9.728; df = 2; р = 0.008), while the highest rate of 40.9% was observed following endoscopic treatment. By the 5th year of follow-up, only 37.5% of patients showed no signs of bleeding following endoscopic procedures. The percentage of patients who did not experience true gastroesophageal variceal rebleeding amounted to 44%, 76%, and 85% following shunt placement, total esophagogastric disconnection, and endoscopic procedures, respectively (p < 0.05).Conclusion. Irrespective of the selected procedure, all patients with cirrhosis suffer from portal rebleeding in the longterm period. However, the lowest rebleeding rate is observed following portosystemic shunt placement.
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来源期刊
Annals of HPB Surgery
Annals of HPB Surgery Medicine-Gastroenterology
CiteScore
0.70
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0.00%
发文量
41
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