社会保障疼痛治疗单位中癌症患者生活质量的相关因素——秘鲁利马

Gloria Pacheco-Feijoó, Luis Podestá-Gavilano, Katherin Quevedo-Porras, José Amado-Tineo
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摘要

生活质量是姑息治疗中癌症患者主要关注的问题之一;然而,对这些患者生活质量的研究是有限的。目的:探讨姑息治疗中影响肿瘤患者生活质量的相关因素。方法:对2021年期间在疼痛和姑息治疗中心接受治疗的184例癌症患者进行观察性分析研究。因变量为生活质量;自变量为年龄、性别、教育程度、职业、肿瘤诊断、病程和分期。以95%的置信水平计算粗患病率(RP)和校正患病率(aRP)。结果:中位年龄63岁,66.3%为女性。与生活质量相关的因素有乳腺癌(aRP=1.21;95% ci: 1.07-1.36;p <0.010),前列腺癌(aRP=1.36;95% ci: 1.18-1.56;p <0.010)或多发性骨髓瘤(aRP=1.33;95% ci: 1.15-1.53;p <0.010),与其他癌症如霍奇金淋巴瘤、胃癌、肾癌或胰腺癌相比;病程大于36个月(aRP=1.13;95% ci: 1.01-1.27;p=0.040),ⅲ期(aRP=1.30;95% ci: 1.19-1.42;P <0.010)也与生活质量有关。结论:与患有其他类型癌症相比,与生活质量相关的因素是患有乳腺癌、前列腺癌或多发性骨髓瘤;除了病程超过36个月和III期与I/II期相比。
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Factors associated with quality of life in cancer patients in a social security pain therapy unit - Lima, Peru
Introduction: Quality of life is one of the main concerns for cancer patients in palliative care; however, studies on quality of life in these patients are limited. Objective: To determine the factors associated with quality of life in patients with oncological disease in palliative care. Methods: Observational, analytical study in 184 cancer patients treated in a Pain and Palliative Care Unit during 2021. The dependent variable was quality of life; independent variables were age, sex, education level, occupation, oncological diagnosis, disease duration, and stage. Crude (RP) and adjusted (aRP) prevalence ratios were calculated with a 95% confidence level. Results: The median age was 63 years, and 66.3% were female. Factors associated with quality of life were breast cancer (aRP=1.21; 95% CI: 1.07-1.36; p!<0.010), prostate cancer (aRP=1.36; 95% CI: 1.18-1.56; p!<0.010), or multiple myeloma (aRP=1.33; 95% CI: 1.15-1.53; p!<0.010), compared to other cancers such as Hodgkin's lymphoma, stomach, kidney, or pancreatic cancer; disease duration longer than 36 months (aRP=1.13; 95% CI: 1.01-1.27; p=0.040), and stage III (aRP=1.30; 95% CI: 1.19-1.42; p!<0.010) were also associated with quality of life. Conclusions: Factors associated with quality of life were having breast, prostate, or multiple myeloma cancer, compared to having another type of cancer; in addition to a disease duration longer than 36 months and stage III compared to stage I/II.
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