孟加拉国一家三级护理医院神经毒性蛇咬伤患者的临床和人口统计资料

Pranab Kumar Mallik, M. R. Amin, M. A. Faiz
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引用次数: 0

摘要

背景:在孟加拉国,尤其是在农村地区,神经毒性蛇咬伤是一种可能导致死亡的重要健康危害。流行病学数据显示,一年内发生70万起蛇咬伤事件,导致6000人死亡。尽管这个问题很关键,但相关文献中的研究有限。因此,为了弥合这一差距并为这一领域提供新的见解,本研究旨在观察孟加拉国三级护理医院神经毒性蛇咬伤的临床和人口统计学特征。方法:本研究是在达卡医学院医院(DMCH)住院部进行的一项基于医院的观察性研究。根据纳入和排除标准,对因神经毒性蛇咬伤而入住DMCH的35名患者进行了检查。伦理问题在整个研究过程中得到了适当的保证。在获得书面知情同意书后,记录专利历史,进行体检,并将数据记录在结构化的病例记录表中。最后,通过SPSS 22对收集的数据进行计算机分析。结果:21~30岁年龄组神经毒性蛇咬伤发生率最高(34.3%)。受试者的平均年龄为32.31±14.33 SD。共鉴定出11条神经毒性蛇,其中眼镜蛇7条,甲鱼4条。吞咽困难、言语困难、复视和呼吸困难分别占11.4%、28.6%、5.7%和37.1%。此外,所有受试者均患有Ptosis(100%),14.3%患有眼外肌麻痹,57.1%患有颈骨折征。此外,60%的患者完全康复,17.1%的患者因并发症康复,但不幸的是,22.9%的患者死亡。结论:Ptosis和颈部骨折是最常见的神经毒性体征。然而,还需要进行更大规模的研究来验证和认可这一发现。
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Clinical and Demographic Profile of Neurotoxic Snake Bite Patients in a Tertiary Care Hospital in Bangladesh
Background:Neurotoxic Snake bite is an important health hazard that may lead to fatality in Bangladesh, particularly in rural areas. Epidemiological data point to 700000 incidences of snake bite resulting in 6000 deaths in a year. Despite the criticality of this issue, limited studies are available in the pertinent literature. Consequently, to bridge the gap and offer fresh insights into this domain, the present study was an effort to observe the clinical and demographic profile of neurotoxic snake bite in tertiary care hospital of Bangladesh. Methods:This research was a hospital based observational study which was conducted at the inpatient department of Medicine in Dhaka Medical College Hospital (DMCH). Thirty five patients admitted in DMCH for neurotoxic snake bite were examined according to the inclusion and exclusion criteria. Ethical issues were ensured properly throughout the study. After obtaining a written informed consent, patents’ history was taken and physical examination was done and data were recorded in structured case record form. In the end, the collected data was analysed by computer via SPSS 22. Results: Neurotoxic snake bite was most frequent (34.3%) in age group 21-30 years. The mean age of the subjects was 32.31 ±14.33 SD. Total 11 Neurotoxic snake was identified and 7 were Cobras and 4 were Kraits. Difficulty in swallowing, difficulty in speech, double vision, and difficulty in breathing were found in 11.4%, 28.6%, 5.7%, and 37.1% of the cases, respectively.  Moreover, all the subjects had Ptosis (100%), 14.3% had external ophthalmoplegia, 57.1% had broken neck sign. Furthermore 60% of the cases recovered completely, 17.1% recovered with complications, but unfortunately 22.9% of the patients died. Conclusion: Ptosis and broken neck signs are the most frequent neurotoxic signs. However, a larger study is needed to validate and approve this finding.
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期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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