冠状动脉微血管疾病各种治疗方法综述

Akshay J Reddy, Nicholas P Iskandar
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摘要

这项研究使我们能够更多地了解Plavix与冠状动脉微血管功能障碍治疗之间的关系。Plavix能够与阿司匹林在双重治疗方法中协同作用,以提高抗血小板治疗效果并减少血小板受体阻断引起的血小板聚集,这是该药物的许多重要优势之一。研究人员发现,由Plavix引起的心血管不良事件风险的平均降低远远超过任何潜在的系统危害。尽管已经表明,目前的护理标准显著降低了微心血管疾病患者的危害,但还需要更多的研究来确保这一标准得到提高。在未来,将患者群体纳入试验而不需要将糖尿病作为一项要求可能会变得更加典型。研究结果可能有偏差,因为糖尿病患者的低密度脂蛋白胆固醇水平通常高于总体人群。为了证实或否认这一说法,需要进行更多的调查。
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A Narrative Review on Various Treatment Methods for Coronary Microvascular Disease
This investigation allowed us to understand more about the relationship between Plavix and the treatment of coronary microvascular dysfunction. The capacity of Plavix to work in tandem with aspirin in a dual treatment approach to improve the anti-platelet therapeutic impact and to lessen platelet aggregation brought on by platelet receptor blockade is one of the drug’s many important advantages. The researchers found that the average reduction in risk of adverse cardiovascular events caused by Plavix much outweighed any potential systemic harm. Although it has been shown that the current standard of care significantly lowers harm among people with micro cardiovascular disease, more study is needed to ensure that this standard is enhanced. It may become more typical in the future to include patient groups in trials without requiring diabetes as a requirement. It is possible that the study results are biased since diabetes patients often have higher LDL cholesterol levels than the overall population. To confirm or deny this claim, more investigation is necessary.
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