土耳其东南部重症监护病房收治的蛇和蝎子中毒患者的严重程度和管理:一项回顾性研究

F. Bozkurt, B. Aydin, T. Tanriverdi, G. Patmano, M. Tercan, A. Kaya
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引用次数: 0

摘要

背景:蛇和蝎子中毒是世界许多地区常见的公共卫生问题。毒蛇和蝎子中毒的患者可能出现危及生命的紧急情况;因此,这些患者可能需要重症监护病房(ICU)随访。我们的目的是介绍在我们三级医院ICU随访的蛇和蝎子中毒患者的人口学和临床特征、治疗方式和短期结果。方法:回顾性检索2010年1月至2019年9月ICU住院的蛇或蝎子中毒患者的病历,使用相关关键词和ICD-10编码对其进行识别。所有ICU住院病例纳入研究分析,无论患者年龄。门诊处理的蝎子和蛇中毒被排除在我们的数据之外。中毒严重程度评分(PSS)系统显示症状和体征,并计算PSS。确定并分析了初级和重症监护治疗方式。结果:本研究共纳入40例患者,其中蛇咬伤25例(62.5%),蝎子螫伤15例(37.5%)。33例(82.5%)和27例(67.5%)患者分别报告了局部和全身效应。大多数患者有疼痛或感觉神经、血液、心血管或代谢系统紊乱。中位PSS为2(0-4),中位ICU住院时间为2天(1-12)。死亡率为2.5%。抗蛇毒血清免疫球蛋白(n=32, %80.0)、全身抗菌药物(n=24, 60%)和扑热息痛(n=21, 52.5%)是最常见的全身用药。结论:我们报告蛇蝎中毒患者多因局部和/或全身性症状而入住ICU进行深入监测和观察。虽然在我们的研究中生命治疗急症和死亡率不常见,但我们认为这些患者应在ICU密切随访。
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Severity and Management of patients with Snake and Scorpion Envenomation Admitted to an Intensive Care Unit in Southeastern Turkey: A retrospective study
Background: Snake and scorpion envenomation is a common public health problem in many regions of the world. Life-threatening emergencies may occur in patients with snake and scorpion envenomation; therefore, these patients may be required intensive care unit (ICU) follow-up. Our objective was to present the demographic and clinical characteristics, treatment modalities and short term outcomes of patients with snake and scorpion envenomation who followed up in our tertiary hospital ICU. Methods: Patient records were retrospectively searched and snake or scorpion envenomation patients with ICU stay were identified with relevant keywords and ICD-10 codes between January 2010 and September 2019. All cases with ICU stay were included for study analysis, regardless of patient age. Scorpion and snake envenomation managed in outpatient clinic were excluded from our data. Poisoning severity score (PSS) system was used to present signs and symptoms and PSS was calculated. Primary and critical care treatment modalities were identified and analyzed. Results: Forty patients (25 with snake bites [62.5%] and 15 with scorpion sting [37.5%]) were included in this retrospective study. Local and systemic effects have been reported in 33 (82.5%) and in 27 patients (67.5%), respectively. Majority of patients suffered from pain or disturbances in sensory neural, hematological, cardiovascular or metabolic systems. Median PSS was 2 (0-4) and median length of stay in ICU was 2 days (1-12). Mortality rate was 2.5%. Antivenom immunoglobulins (n=32, %80.0), systemic antibacterial agents (n=24, 60%), and paracetamol (n=21, 52.5%) were the most common systemically administered treatments. Surgical interventions were performed in 4 patients (10%) Conclusions: We reported that snake and scorpion envenomation were mostly admitted to the ICU with local and/or systemic symptoms for advanced monitoring and observation. Although life treating emergencies and mortality was uncommon in our study, we think that these patients should be closely followed up in ICU.
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期刊介绍: Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.
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