空气污染物浓度与呼吸道疾病住院频率的关系

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-25 Epub Date: 2023-07-21 DOI:10.26444/aaem/169486
Anna Grzywa-Celińska, Adam Krusiński, Katarzyna Dos Santos Szewczyk, Ewa Kurys-Denis, Janusz Milanowski
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引用次数: 0

摘要

引言和目标。烟雾含有细粉尘、非金属氧化物、金属和有机化合物,具有刺激性、致敏性和免疫调节作用,导致呼吸道疾病的发展及其恶化。这项研究的目的是寻找空气污染物浓度与因哮喘、慢性阻塞性肺病或呼吸异常恶化而住院频率之间的关系。材料和方法。入院数据通过医院数字信息系统访问。根据环境保护总局的公开数据库,使用了有关污染物浓度的数据,如PM2.5和PM10、二氧化硫IV、一氧化氮IV、一氧化碳II、苯和臭氧(O3),这些数据每天测量,每小时精确一次。将空气污染物平均浓度的结果与相应时间间隔内的住院率进行比较。后果显示了许多统计上显著的相关性,表明每种测试污染物的浓度增加对住院频率的作用。特别是,COPD和PM 2.5和PM 10、苯和NO 2引起的哮喘以及苯、CO和SO 2引起的呼吸系统疾病的住院频率之间存在强正相关。结论。结果表明,空气污染可能是呼吸道疾病恶化的一个重要的可改变的风险因素,因此避免空气污染在初级预防中起着重要作用。
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Relationship between concentration of air pollutants and frequency of hospitalisations due to respiratory diseases.

Introduction and objective: Smog, which contains fine dusts, non-metal oxides, metals and organic compounds can have irritating, allergenic and immunomodulatory effects leading to the development of respiratory diseases and their exacerbations. The aim of the study was to search for a relationship between concentrations of air pollutants and the frequency of hospitalizations due to exacerbation of asthma, chronic obstructive pulmonary disease, or abnormalitis in breathing.

Material and methods: Hospital admission data was accessed from the hospital digital in-formation system. From the publicly available database of the Chief Inspectorate for Environmental Protection, data concerning the concentrations of pollutants, such as PM2.5 and PM10, sulphur oxide IV (SO2), nitric oxide IV (NO2), carbon monoxide II (CO), benzene and ozone (O3), measured daily with hourly accuracy was used. The results of the average concentrations of air pollutants were compared with the rates of hospitalization in the corresponding time intervals.

Results: A number of statistically significant correlations were shown indicating the role of increased concentrations of each of the tested contaminants in the frequency of hospitalizations. In particular, strongly positive correlations were shown between the frequency of hospitalizations due to COPD and PM2.5 and PM10, asthma with benzene and NO2, and for respiratory disorders in general with benzene, CO and SO2.

Conclusions: The results indicate that air pollution can be a significant modifiable risk factor for exacerbations of respiratory diseases and therefore its avoidance plays an important role in primary prevention.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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