中性粒细胞CD64作为一种新兴生物标志物在新生儿败血症评估中的作用

D. Paul, Abu Naser Ibne Sattar, A. Roy, S. Islam, Sheuly Ferdousi, T. Paul, Mesbah U. Ahmed, S. Sikder
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引用次数: 1

摘要

结果:与对照组(8.19±3.64)相比,CD64在患者中性粒细胞上的表达率较高(67.73±24.74),在培养阳性脓毒症中的表达率(76.25±29.07)高于培养阴性脓毒症(42.21±33.24),分别为33.3%、92.3%和71.7%。
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Role of neutrophil CD64 as an emerging biomarker in the evaluation of neonatal sepsis
Results: We found high percentage of expression of CD64 on neutrophils in patients (67.73 ± 24.74) when compared with controls (8.19 ± 3.64) and also their percentage of expression was higher in culture positive sepsis (76.25 ± 29.07) than culture negative sepsis (42.21 ± 33.24). In the present study, I/T ratio >0.2 had a sensitivity, specificity, PPV, NPV and accuracy i.e. 70.0%, 72.0%, 33.3%, 92.3% and 71.7% respectively.
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