循环性死亡供体在儿童肝移植中的应用

Q4 Medicine Transplantation Reports Pub Date : 2023-06-01 DOI:10.1016/j.tpr.2023.100128
Veysel Umman, Murat Zeytunlu, Sukru Emre
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引用次数: 1

摘要

随着技术的进步,使用成熟和新颖的免疫抑制疗法,以及更好的术前和术后护理,肝移植患者的总体生存率很高,等待名单死亡率已成为儿科终末期肝病患者的主要问题。器官供体不足已经成为一个具有挑战性的问题,特别是在儿科患者群体中,对于他们来说,供体或移植物的大小匹配更难实现。为扩大供体库,缩小供体器官供需缺口,循环性死亡供体的使用已成比例增加。在本章中,我们旨在讨论DCD在儿童肝移植中的当前实践、问题和结果,以及未来改善结果的策略。
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Use of donation after circulatory death donors in pediatric liver transplantation

After advancement of technical aspects, use of well-established and novel immunosuppressive therapies, and better pre and postoperative care, which resulted in high overall survival rates with liver transplantation, waiting list mortality has become the main issue for pediatric patients with end stage liver disease. Insufficient organ donors have become a challenging issue especially in the pediatric patient population, for whom size match of donor or graft is harder to achieve. In order to expand the donor pool and decrease the gap between the demand and supply of donor organs, use of donation after circulatory death (DCD) donors have been proportionally increased. In this chapter we aim to discuss current practices, issues and outcomes with DCD in pediatric liver transplantation, as well as future strategies for improvement of results.

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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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