在高达200mev的质子诱导核反应中产生11C, 13N和15O

IF 2.8 1区 物理与天体物理 Q2 PHYSICS, NUCLEAR Nuclear Data Sheets Pub Date : 2023-02-01 DOI:10.1016/j.nds.2023.01.004
T. Rodríguez-González , C. Guerrero , C.M. Bäcker , J. Bauer , C. Bäumer , S. Brons , W. Jentzen , M.C. Jiménez-Ramos , M.Á. Millán-Callado , C. Schömers , B. Timmermann , J.M. Quesada , R. Capote
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引用次数: 0

摘要

从质子入射能量阈值到200 MeV,测量了光正电子发射器11C (t1/2=20.36 min)、13N (t1/2=9.97 min)和15O (t1/2=122 s)在人体主要相关成分(C、N和O)上的质子诱导反应的产生截面。这是通过德国临床质子治疗中心WPE(埃森)和HIT(海德堡)的两个互补实验完成的。在第一个案例中,多箔激活技术与PET成像相结合,这是CNA (Seville, Spain)先前开发的一种方法。在第二个实验中,针对低于50兆电子伏的能量,用传统的LaBr3探测器测量了单个箔的激活。在这两种情况下,原子能机构监测反应natCu(p,x)63Zn数据都用于验证目的。给出了在200 MeV的人体组织质子诱导反应中产生光-正电子发射体11C、13N和15O的最完整和准确的激发函数集。这些数据是建立核反应模型所必需的,对提高质子放射治疗中PET范围验证的准确性至关重要。测量了七种激发函数:12C(p,x)11C, 14N(p,x)11C, 14N(p,x)13N, 14N(p,x)13N, 14N(p,γ)15O, 16O(p,x)11C, 16O(p,x)13N和16O(p,x)15O,质子入射能量高达200 MeV。
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Production of 11C, 13N and 15O in proton-induced nuclear reactions up to 200 MeV

Production cross sections of light positron emitters 11C (t1/2=20.36 min), 13N (t1/2=9.97 min) and 15O (t1/2=122 s) have been measured for proton-induced reactions on the main relevant constituents of the human body (C, N and O) from threshold up to 200 MeV of proton incident energy. This has been accomplished by means of two complementary experiments at the clinical proton treatment centers WPE (Essen) and HIT (Heidelberg), both in Germany. In the first case, the multi-foil activation technique was combined with PET imaging, a methodology previously developed at CNA (Seville, Spain). In the second experiment, aimed at energies below 50 MeV, the activation of single foils was measured with conventional LaBr3 detectors. In both cases the IAEA monitor reaction natCu(p,x)63Zn data was used for validation purposes.

The most complete and accurate set of excitation functions for the production of light-positron emitters 11C, 13N and 15O in proton induced reactions on human tissue up to 200 MeV is presented. These data are needed for nuclear reaction model development and are extremely important to improve the accuracy of the PET range verification in proton radiotherapy. Seven excitation functions have been measured: 12C(p,x)11C, 14N(p,x)11C, 14N(p,x)13N, 14N(p,γ)15O, 16O(p,x)11C, 16O(p,x)13N and 16O(p,x)15O up to 200 MeV of proton incident energy.

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来源期刊
Nuclear Data Sheets
Nuclear Data Sheets 物理-物理:核物理
CiteScore
7.80
自引率
5.40%
发文量
22
审稿时长
>12 weeks
期刊介绍: The Nuclear Data Sheets are current and are published monthly. They are devoted to compilation and evaluations of experimental and theoretical results in Nuclear Physics. The journal is mostly produced from Evaluated Nuclear Structure Data File (ENSDF), a computer file maintained by the US National Nuclear Data Center
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