T. Rodríguez-González , C. Guerrero , C.M. Bäcker , J. Bauer , C. Bäumer , S. Brons , W. Jentzen , M.C. Jiménez-Ramos , M.Á. Millán-Callado , C. Schömers , B. Timmermann , J.M. Quesada , R. Capote
{"title":"在高达200mev的质子诱导核反应中产生11C, 13N和15O","authors":"T. Rodríguez-González , C. Guerrero , C.M. Bäcker , J. Bauer , C. Bäumer , S. Brons , W. Jentzen , M.C. Jiménez-Ramos , M.Á. Millán-Callado , C. Schömers , B. Timmermann , J.M. Quesada , R. Capote","doi":"10.1016/j.nds.2023.01.004","DOIUrl":null,"url":null,"abstract":"<div><p>Production cross sections of light positron emitters <sup>11</sup>C (t<sub>1</sub><sub>/</sub><sub>2</sub>=20.36 min), <sup>13</sup>N (t<sub>1</sub><sub>/</sub><sub>2</sub>=9.97 min) and <sup>15</sup>O (t<sub>1</sub><sub>/</sub><sub>2</sub>=122 s) have been measured for proton-induced reactions on the main relevant constituents of the human body (C, N and O) from threshold up to 200 MeV of proton incident energy. This has been accomplished by means of two complementary experiments at the clinical proton treatment centers WPE (Essen) and HIT (Heidelberg), both in Germany. In the first case, the multi-foil activation technique was combined with PET imaging, a methodology previously developed at CNA (Seville, Spain). In the second experiment, aimed at energies below 50 MeV, the activation of single foils was measured with conventional LaBr<sub>3</sub> detectors. In both cases the IAEA monitor reaction <sup>nat</sup>Cu(p,x)<sup>63</sup>Zn data was used for validation purposes.</p><p>The most complete and accurate set of excitation functions for the production of light-positron emitters <sup>11</sup>C, <sup>13</sup>N and <sup>15</sup>O in proton induced reactions on human tissue up to 200 MeV is presented. These data are needed for nuclear reaction model development and are extremely important to improve the accuracy of the PET range verification in proton radiotherapy. Seven excitation functions have been measured: <sup>12</sup>C(p,x)<sup>11</sup>C, <sup>14</sup>N(p,x)<sup>11</sup>C, <sup>14</sup>N(p,x)<sup>13</sup>N, <sup>14</sup>N(p,<em>γ</em>)<sup>15</sup>O, <sup>16</sup>O(p,x)<sup>11</sup>C, <sup>16</sup>O(p,x)<sup>13</sup>N and <sup>16</sup>O(p,x)<sup>15</sup>O up to 200 MeV of proton incident energy.</p></div>","PeriodicalId":49735,"journal":{"name":"Nuclear Data Sheets","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Production of 11C, 13N and 15O in proton-induced nuclear reactions up to 200 MeV\",\"authors\":\"T. Rodríguez-González , C. Guerrero , C.M. Bäcker , J. Bauer , C. Bäumer , S. Brons , W. Jentzen , M.C. Jiménez-Ramos , M.Á. Millán-Callado , C. Schömers , B. Timmermann , J.M. Quesada , R. Capote\",\"doi\":\"10.1016/j.nds.2023.01.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Production cross sections of light positron emitters <sup>11</sup>C (t<sub>1</sub><sub>/</sub><sub>2</sub>=20.36 min), <sup>13</sup>N (t<sub>1</sub><sub>/</sub><sub>2</sub>=9.97 min) and <sup>15</sup>O (t<sub>1</sub><sub>/</sub><sub>2</sub>=122 s) have been measured for proton-induced reactions on the main relevant constituents of the human body (C, N and O) from threshold up to 200 MeV of proton incident energy. This has been accomplished by means of two complementary experiments at the clinical proton treatment centers WPE (Essen) and HIT (Heidelberg), both in Germany. In the first case, the multi-foil activation technique was combined with PET imaging, a methodology previously developed at CNA (Seville, Spain). In the second experiment, aimed at energies below 50 MeV, the activation of single foils was measured with conventional LaBr<sub>3</sub> detectors. In both cases the IAEA monitor reaction <sup>nat</sup>Cu(p,x)<sup>63</sup>Zn data was used for validation purposes.</p><p>The most complete and accurate set of excitation functions for the production of light-positron emitters <sup>11</sup>C, <sup>13</sup>N and <sup>15</sup>O in proton induced reactions on human tissue up to 200 MeV is presented. These data are needed for nuclear reaction model development and are extremely important to improve the accuracy of the PET range verification in proton radiotherapy. Seven excitation functions have been measured: <sup>12</sup>C(p,x)<sup>11</sup>C, <sup>14</sup>N(p,x)<sup>11</sup>C, <sup>14</sup>N(p,x)<sup>13</sup>N, <sup>14</sup>N(p,<em>γ</em>)<sup>15</sup>O, <sup>16</sup>O(p,x)<sup>11</sup>C, <sup>16</sup>O(p,x)<sup>13</sup>N and <sup>16</sup>O(p,x)<sup>15</sup>O up to 200 MeV of proton incident energy.</p></div>\",\"PeriodicalId\":49735,\"journal\":{\"name\":\"Nuclear Data Sheets\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2023-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nuclear Data Sheets\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0090375223000042\",\"RegionNum\":1,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSICS, NUCLEAR\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nuclear Data Sheets","FirstCategoryId":"101","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0090375223000042","RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSICS, NUCLEAR","Score":null,"Total":0}
Production of 11C, 13N and 15O in proton-induced nuclear reactions up to 200 MeV
Production cross sections of light positron emitters 11C (t1/2=20.36 min), 13N (t1/2=9.97 min) and 15O (t1/2=122 s) have been measured for proton-induced reactions on the main relevant constituents of the human body (C, N and O) from threshold up to 200 MeV of proton incident energy. This has been accomplished by means of two complementary experiments at the clinical proton treatment centers WPE (Essen) and HIT (Heidelberg), both in Germany. In the first case, the multi-foil activation technique was combined with PET imaging, a methodology previously developed at CNA (Seville, Spain). In the second experiment, aimed at energies below 50 MeV, the activation of single foils was measured with conventional LaBr3 detectors. In both cases the IAEA monitor reaction natCu(p,x)63Zn data was used for validation purposes.
The most complete and accurate set of excitation functions for the production of light-positron emitters 11C, 13N and 15O in proton induced reactions on human tissue up to 200 MeV is presented. These data are needed for nuclear reaction model development and are extremely important to improve the accuracy of the PET range verification in proton radiotherapy. Seven excitation functions have been measured: 12C(p,x)11C, 14N(p,x)11C, 14N(p,x)13N, 14N(p,γ)15O, 16O(p,x)11C, 16O(p,x)13N and 16O(p,x)15O up to 200 MeV of proton incident energy.
期刊介绍:
The Nuclear Data Sheets are current and are published monthly. They are devoted to compilation and evaluations of experimental and theoretical results in Nuclear Physics. The journal is mostly produced from Evaluated Nuclear Structure Data File (ENSDF), a computer file maintained by the US National Nuclear Data Center