EB病毒相关淋巴增生性疾病的诊治进展

Pub Date : 2020-03-25 DOI:10.3760/CMA.J.CN115356-20200105-00011

Hang Zhou, Yuhan Ma

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引用次数: 0

摘要

EB病毒是一种潜在的致癌病毒。大约95%的健康人感染了EB病毒，并终生携带。EBV可诱导宿主细胞克隆和转化。大约2%的肿瘤与EB病毒感染有关。近年来，EBV诱导的淋巴细胞克隆转化及与EBV相关的淋巴细胞增殖性疾病的诊断和治疗取得了一定进展。关键词：疱疹病毒4型，人；淋巴瘤；转型；免疫治疗；细胞疗法

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Diagnosis and treatment progress of EB virus-related lymphoproliferative diseases

EB virus (EBV) is a potential oncogenic virus. About 95% of healthy people are infected with EBV and carry it for all life. EBV can induce host cells clonization and transformation. About 2% of tumors are related to EBV infection. In recent years, EBV-induced lymphocyte clonal transformation and the diagnosis and treatment of EBV-related lymphoproliferative diseases have got some progress. Key words: Herpesvirus 4, human; Lymphoma; Transformation; Immunotherapy; Cellular therapy

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