罕见复发的布尔哈夫综合征:一种替代手术入路病例报告

E. Yii, E. Wong, S. Joglekar, M. Johnson
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摘要

布尔哈夫综合征是一种罕见的疾病。它与高发病率和高死亡率有关。我们描述了一个非常罕见的食道穿孔再次发生在同一患者,四年后第一次发病率没有明确的病因除了巴雷特食道。我们的病人表现为多次呕吐和恶心,随后出现急性上腹部和右上腹疼痛。布尔哈夫综合征是一种发病率和死亡率都很高的疾病。在非常罕见的情况下,据报道在同一患者中出现两次,就像我们的病例一样。第一个食管穿孔经右胸入路修复,第二个穿孔经经典腹部入路成功修复。据我们所知,这是文献中第一次描述这种治疗方法。进行了一项总结性文献综述,确定了11例报告病例,发现除了中度至重度酒精摄入外,缺乏具体的风险因素,以及一组非特异性的再表现症状。因此,考虑到24小时内手术时间是显著改善预后的已知因素,我们建议对有原发性布尔哈夫综合征病史且有反复发作的模棱两可症状的患者进行影像学检查时降低临床阈值。
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A rare incidence of recurrent Boerhaave’s syndrome: an alternative operative approach—case report
Boerhaave’s syndrome is a rare condition. It is associated with a high morbidity and mortality. We describe a very rare incidence of oesophageal perforation that occurred again in the same patient, four years following the first incidence with no clear causative factor apart from Barrett’s oesophagus. Our patient presented with multiple vomits and nausea followed by acute epigastric and right upper quadrant pain. Boerhaave’s syndrome is a condition with a high morbidity and mortality rate. In very rare cases, it has been reported to occur twice in the same patient as was seen in our case. The first oesophageal perforation was repaired via a right thoracic approach while the second perforation was successfully repaired via a classical abdominal approach. To our knowledge this is the first in the literature to describe this approach for this condition. A summative a literature review was performed which identified eleven reported cases and found a lack of specific risk factors apart from moderate to heavy alcohol intake, and a non-specific set of symptoms for re-presentations. Thus, we suggest having a lower clinical threshold for imaging patients with a history of primary Boerhaave’s syndrome who present with equivocal symptoms of a recurrent episode given that time to surgery within 24 hours is a known factor for significantly improved outcomes.
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