肝功能障碍患者营养管理原则综述

Livers Pub Date : 2023-04-04 DOI:10.3390/livers3020013
E. M. Elsebaie, Alyaa Nasr Abdel-Fattah, Nagwa Awad Bakr, Kadry Mohamed Attalah, Abdel-Hady Ahmed Aweas
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引用次数: 0

摘要

根据研究,肝脏在体内发挥生理功能的能力决定了肝病患者的饮食。营养不良是由于慢性肝功能紊乱导致肝脏无法代谢营养物质。目的:回顾饮食和膳食补充剂对肝功能紊乱的营养管理数据。结果:根据临床研究,营养不良在肝硬化患者中尤其普遍。由于营养不良对发病率、死亡率和生活质量有显著的负面影响,因此评估所有肝硬化患者至关重要,无论病因或严重程度如何。对于没有达到营养目标的患者,可以建议使用补充肠内营养。详细的营养和运动评估将有助于制定包括饮食和运动计划在内的个性化治疗计划。饮食治疗应概述每日卡路里目标,重点关注高质量蛋白质,并解决任何维生素和微量营养素缺乏问题,饮食中应富含这些营养素或补充剂。结论:虽然有证据支持使用特定的限制性饮食计划和膳食补充剂来治疗肝病,但在大型随机对照临床试验中得到证实之前,这些发现应被视为初步发现。
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Principles of Nutritional Management in Patients with Liver Dysfunction—A Narrative Review
According to studies, the liver’s ability to perform its physiological functions in the body determines the diet of patients with liver diseases. Malnutrition results from the liver’s inability to metabolize nutrients as a result of chronic liver dysfunctions. Objectives: Reviewing the data about diets and dietary supplements that manage liver dysfunctions nutritionally. Results: Malnutrition is particularly prevalent in cirrhosis patients, according to clinical studies. Because malnutrition has a significant negative impact on morbidity, mortality, and quality of life, it is crucial to evaluate all cirrhosis patients, regardless of etiology or severity. A term of supplemental enteral nutrition may be suggested for patients who do not achieve their nutritional objectives. A detailed nutritional and exercise assessment will enable the development of an individualized treatment plan that includes dietary and exercise plans. The dietary treatment should outline daily calorie targets with a focus on high-quality protein and address any vitamin and micronutrient deficiencies, with a diet high in those nutrients or supplements. Conclusions: While there is evidence to support the use of particular restricted dietary plans and dietary supplements to manage liver diseases, these findings should be regarded as preliminary until they are confirmed in larger randomized controlled clinical trials.
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