{"title":"磷化铝中毒;生存案例","authors":"N. Ramadan","doi":"10.22038/APJMT.2019.12769","DOIUrl":null,"url":null,"abstract":"Background: Aluminum phosphideis a commonly used as a pesticide in Egypt and other agricultural countries to protect grains from pests. Phosphine gas (PH3) is a highly toxic gas, which is released when the tablet is exposed to humidity, causing cardiogenic shock and severe metabolic acidosis. Case presentation: A 22-year-old female patient with history of ingestion of 1 tablet of Aluminum phosphide presented with recurrent vomiting, severe hypotension and metabolic acidosis. Discussion: Although Aluminum phosphide is considered a highly toxic substance and its rate of death is very high, this case survived even after development of severe toxic manifestations like hypotension and severe metabolic acidosis. Conclusion: Aluminium Phosphide is a highly effective insecticide and rodenticide. However, it is highly toxic with high mortality rate if ingested. It produces severe metabolic acidosis and cardiogenic shock with no available antidote, so management may be the only supportive treatment","PeriodicalId":30463,"journal":{"name":"Asia Pacific Journal of Medical Toxicology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Aluminum Phosphide Poisoning; a Case of Survival\",\"authors\":\"N. Ramadan\",\"doi\":\"10.22038/APJMT.2019.12769\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Aluminum phosphideis a commonly used as a pesticide in Egypt and other agricultural countries to protect grains from pests. Phosphine gas (PH3) is a highly toxic gas, which is released when the tablet is exposed to humidity, causing cardiogenic shock and severe metabolic acidosis. Case presentation: A 22-year-old female patient with history of ingestion of 1 tablet of Aluminum phosphide presented with recurrent vomiting, severe hypotension and metabolic acidosis. Discussion: Although Aluminum phosphide is considered a highly toxic substance and its rate of death is very high, this case survived even after development of severe toxic manifestations like hypotension and severe metabolic acidosis. Conclusion: Aluminium Phosphide is a highly effective insecticide and rodenticide. However, it is highly toxic with high mortality rate if ingested. It produces severe metabolic acidosis and cardiogenic shock with no available antidote, so management may be the only supportive treatment\",\"PeriodicalId\":30463,\"journal\":{\"name\":\"Asia Pacific Journal of Medical Toxicology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asia Pacific Journal of Medical Toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22038/APJMT.2019.12769\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asia Pacific Journal of Medical Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/APJMT.2019.12769","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Background: Aluminum phosphideis a commonly used as a pesticide in Egypt and other agricultural countries to protect grains from pests. Phosphine gas (PH3) is a highly toxic gas, which is released when the tablet is exposed to humidity, causing cardiogenic shock and severe metabolic acidosis. Case presentation: A 22-year-old female patient with history of ingestion of 1 tablet of Aluminum phosphide presented with recurrent vomiting, severe hypotension and metabolic acidosis. Discussion: Although Aluminum phosphide is considered a highly toxic substance and its rate of death is very high, this case survived even after development of severe toxic manifestations like hypotension and severe metabolic acidosis. Conclusion: Aluminium Phosphide is a highly effective insecticide and rodenticide. However, it is highly toxic with high mortality rate if ingested. It produces severe metabolic acidosis and cardiogenic shock with no available antidote, so management may be the only supportive treatment
期刊介绍:
Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.