转诊医院新冠肺炎患者的临床特征、影像学、实验室结果和严重程度

Bekti Safarini, M. Arif, Danis Pertiwi, Santika Puji, Rahayu Wijaya, Suryani Yuliyanti, Ksenija Bogoeva-Kostovska
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引用次数: 0

摘要

背景:新冠肺炎大流行由于病例数高且没有具体治疗而成为全球健康问题。此外,由于公布的数据和诊断测试有限,诊断也很困难。目的:本研究的目的是确定转诊医院的人口统计学、临床特征、实验室结果、放射学结果以及与新冠肺炎严重程度相关的因素。方法:在2020年3月至10月期间对新冠肺炎确诊患者进行描述性分析研究。从医疗记录中收集数据,以确定患者人口统计学、临床症状、合并症、实验室、胸部X光检查和治疗24小时时的首次疾病严重程度。结果:研究期间有79名(59%)男性和55名(41%)女性患者。临床症状为发热103例(77%),咳嗽100例(75%),气短88例(66%),合并糖尿病18例(13%),高血压24例(18%),心脏病20例(15%)。患者的实验室特征为淋巴细胞减少85例(63%)和C反应蛋白升高82例(61%)。患者的放射学影像学表现多为新冠肺炎非典型。影响新冠肺炎严重程度的因素是年龄、合并糖尿病和高血压。结论:大多数症状严重的病例都是老年人、有合并糖尿病和心脏病病史以及实验室结果异常。
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Clinical Features, Imaging, Laboratory Result, and Severity of COVID-19 Patients in Referral Hospital
BACKGROUND: COVID-19 pandemic became a global health problem due to the high number of cases and no specific treatment. Furthermore, the diagnosis was difficult due to limited publication data and diagnostic tests. AIM: The aim of this study was to determine the demographics, clinical features, laboratory results, radiological results, and factors related to the severity of COVID-19 at a referral hospital. METHODS: A descriptive analytic study of confirmed COVID-19 patients was conducted during March–October 2020. Data were collected from the medical records to determine the patient demographics, clinical symptoms, comorbidities, laboratory, chest X-ray, and first illness severity at 24 h of treatment. RESULTS: There were 79 (59%) male and 55 (41%) female patients during the study. The clinical symptoms were fever 103 (77%), cough 100 (75%),  shortness of breath 88 (66%), comorbidities of diabetes mellitus 18 (13%), hypertension 24 (18%), and heart disease 20 (15%). The patient’s laboratory profiles were lymphopenia 85 (63%) and increased C-reactive protein 82 (61%). The radiology imaging of the patients was mostly atypical of COVID-19. Factors that influence the severity of COVID-19 are age, comorbid diabetes, and hypertension CONCLUSION: Most cases with severe symptoms are old age, a history of comorbid diabetes mellitus and heart disease, and abnormal laboratory results.
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期刊介绍: Open Access Macedonian Journal of Medical Sciences (OAMJMS) [formerly known as Macedonian Journal of Medical Sciences] is a top-tier open access medical science journal published by the ID Design 2012/DOOEL Skopje, Rajko Zhinzifov No 48, 1000 Skopje, Republic of Macedonia. OAMJMS is an international, modern, general medical journal covering all areas in the medical sciences, from basic studies to large clinical trials and cost-effectiveness analyses. We publish mostly human studies that substantially enhance our understanding of disease epidemiology, etiology, and physiology; the development of prognostic and diagnostic technologies; trials that test the efficacy of specific interventions and those that compare different treatments; and systematic reviews. We aim to promote translation of basic research into clinical investigation, and of clinical evidence into practice. We publish occasional studies in animal models when they report outstanding research findings that are highly clinically relevant. Our audience is the international medical community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world. OAMJMS is published quarterly online version. The Open Access Macedonian Journal of Medical Sciences (OAMJMS) publishes Medical Informatics, Basic Science, Clinical Science, Case Report, Brief Communication, Public Health, Public Policy, and Review Article from all fields of medicine and related fields. This journal also publishes, continuously or occasionally, the bibliographies of the members of the Society, medical history, medical publications, thesis abstracts, book reviews, reports on meetings, i­n­formation on future meetings, important events and dates, and various headings which contribute to the development of the corresponding scientific field.
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