尘肺合并慢性阻塞性肺疾病综合治疗对采矿和钢铁行业工人某些中毒指标的影响

IF 5.3 2区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Environmental Health Pub Date : 2021-02-01 DOI:10.32402/DOVKIL2021.01.042
R. V. Rubtsov, Kryvyi Rih
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引用次数: 0

摘要

目的:以中毒指标为指标,对矿冶、钢铁行业尘肺合并慢性阻塞性肺疾病的综合治疗效果进行评价,评价对该职业病的防治措施。结果:通过对患者、采矿者和钢铁工人进行支气管扩张剂、粘膜调节剂、抗炎剂或复合维生素药物的治疗,以及在1.3大气压下的高压氧治疗,可以降低炎症过程的活性,这与外周血白细胞总数、它们的刺状和分段亚群的含量有关。大多数中毒指标均有所下降:中毒白细胞指数、粒细胞-粒细胞指数、一般中毒指数、异位指数、白细胞与红细胞沉降率比值指数,这表明在中毒现象受到抑制的同时,全身炎症活性有所下降。与其他职业性肺部病理患者相比,综合治疗导致分叶性和刺状白细胞含量下降更为显著,主要整体中毒指标:中毒白细胞指数、粒细胞-粒细胞指数、综合指数下降更为显著。因此,对采矿和钢铁工业工人尘肺合并慢性阻塞性肺疾病的综合治疗是防治这一职业性肺部病变措施体系中的重要环节。结论:对采矿和钢铁行业的尘肺合并慢性阻塞性肺疾病的工人进行综合治疗,使用支气管扩张剂、粘膜调节剂、雾化器给药抗炎剂、肌肉注射复合维生素B药物。此外,高压氧的会话导致一些炎症指标和中毒指标的改善,这是一个预测疾病的积极进程。对工人进行的综合治疗结果的评估表明,中毒过程具有显著的积极动态,并且可以将这种治疗视为旨在治疗和预防这种职业性肺病的措施系统中的一个重要环节。
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The impact of the comprehensive treatment of the pneumoconiosis combined with the chronic obstructive pulmonary disease on some intoxication indicators in ore mining and iron and steel industry workers
Objective:We studied the efficiency of the comprehensive treatment of ore mining and iron and steel industry workers having the pneumoconiosis combined with chronic obstructive pulmonary disease in terms of intoxication indicators as an assessment of measures aimed at treatment and prevention of this occupational pulmonary pathology. Results: It was established that conducted treatment in the patients, ore mining and iron and steel industry workers with the use of bronchodilator, mucoregulator, anti-inflammatory agent of a complex vitamin medication, as well as sessions of hyperbaric oxygenation at 1.3 atm led to a decrease in the activity of inflammation processes with regard to the content in the peripheral blood of the total number of leukocytes, their stab and segmented subpopulations, and a decrease in most intoxication indices: the leukocytic index of intoxication, the granulocytic-agranulocytic index, the general index of intoxication, the sinistroposition index, the index of the ratio of leukocytes to erythrocyte sedimentation rate, which indicates a decrease in the systemic inflammation activity with the simultaneous suppression of intoxication phenomena. In comparison with the patients with other occupational lung pathology, the comprehensive treatment led to a more significant decrease in the content of segmented and stab leukocytes, as well as the main integral intoxication indices: the leukocytic index of intoxication, the granulocytic-agranulocytic index, and the general index. Thus, the comprehensive treatment of ore mining and iron and steel industry workers having the pneumoconiosis combined with the chronic obstructive pulmonary disease is an important link in the system of measures aimed at treatment and prevention ofthis occupational pulmonary pathology. Conclusions: In the ore mining and iron and steel industry workers having the pneumoconiosis combined with the chronic obstructive pulmonary disease,the comprehensive treatment with the use of bronchodilator, mucoregulator, nebulizer-administered anti-inflammatory agent, a complex vitamin B medication administered intramuscularly, as well as sessions of hyperbaric oxygenation led to an improvement in some inflammation indicators and intoxication indices which is a predictor of a positive course of the disease. The assessment of the results of the conducted comprehensive treatment of the workers indicates a significant positive dynamics of intoxication processes and makes it possible to regard this treatment as an important link in the system of measures aimed at treatment and preventionofthisoccupational pulmonary disease.
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来源期刊
Environmental Health
Environmental Health 环境科学-公共卫生、环境卫生与职业卫生
CiteScore
10.10
自引率
1.70%
发文量
115
审稿时长
3.0 months
期刊介绍: Environmental Health publishes manuscripts on all aspects of environmental and occupational medicine and related studies in toxicology and epidemiology. Environmental Health is aimed at scientists and practitioners in all areas of environmental science where human health and well-being are involved, either directly or indirectly. Environmental Health is a public health journal serving the public health community and scientists working on matters of public health interest and importance pertaining to the environment.
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