外伤性颅底脑脊液瘘的手术修复指征

B. Saberi
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摘要

在颅底创伤的情况下,有一些手术修复脑脊液瘘的指征。采用保守治疗方法治疗脑脊液漏时发生脑膜炎、保守治疗失败、肺炎球菌性和持续性脑脊液漏、迟发性脑脊液渗漏、穿透性创伤中的脑脊液渗漏、复发性脑脊液渗漏和前颅底严重缺损伴颅骨缺损的脑疝是一些手术指征。如果在受伤后的七到十天内,尽管进行了腰部引流,但仍会出现脑脊液渗漏,保守治疗将不再有效,应对脑脊液渗漏进行手术修复,外脑突出和穿透性损伤是早期手术的适应症,在这种情况下不应考虑保守治疗。手术修复的最佳时间取决于各种因素,如脑膜炎发展的持续风险和颅底暴露期间额叶回缩的风险,因为创伤会导致脑组织肿胀。外伤发生后,额叶肿胀将在约10天内减少,从而使足够的回缩暴露前颅底。5对于外伤性耳漏,通常不需要手术修复,因为它将在受伤后约14天内解决。6,7由于这一事实,脑脊液耳漏的保守治疗应在损伤后较长时间内考虑,在少数情况下,这种保守治疗策略会失败,可以考虑手术修复。8
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Indications for operative repair of the traumatic skull base CSF fistula
There are some indications for operative repair of the CSF fistula in the skull base trauma setting. Meningitis development while treating the CSF leakage with a conservative treatment method, failure of the conservative treatment, pneumocephalus and persistent leakage of the CSF, delayed CSF leakage, CSF leakage in penetrating trauma, recurrent CSF leakage and severe defect in the anterior skull base with brain herniation through the defect of the skull, are some indications for operation. In case there would be CSF leakage in spite of lumbar drainage in more than seven to ten days after the time of the injury, conservative therapy would not be effective anymore and there should be operative repair to be done for the CSF leakage.4 Having a high risk for developing meningitis, delayed CSF leakage, pneumocephalus and large dural tear, external brain herniation and penetrating injuries are the indications for early surgery which conservative therapy should not be considered in such cases. The best time for surgical repair depends on various factors like ongoing risk for meningitis development and risk of frontal lobe retraction during skull base exposure when there would be a swelling in the brain tissue due to the trauma. Frontal lobe swellings would be decreased in about 10 days after the occurrence of trauma, which allow enough retraction to expose anterior skull base.5 For traumatic otorrhea, surgical repair is usually not necessary since it would be resolved in about 14 days after the injury.6,7 Because of this fact, conservative management of CSF otorrhea should be considered for longer periods after the injury and in few cases which such conservative treatment strategy would be failed, operative repair can be considered.8
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